ENSMUSG00000051111


Mus musculus

Features
Gene ID: ENSMUSG00000051111
  
Biological name :Sv2c
  
Synonyms : Q69ZS6 / Sv2c / synaptic vesicle glycoprotein 2c
  
Possible biological names infered from orthology : Q496J9
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: D1
Gene start: 95954594
Gene end: 96132577
  
Corresponding Affymetrix probe sets: 10411274 (MoGene1.0st)   1453715_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000138317
Ensembl peptide - ENSMUSP00000124473
NCBI entrez gene - 75209     See in Manteia.
MGI - MGI:1922459
RefSeq - NM_029210
RefSeq Peptide - NP_083486
swissprot - A2RSH4
swissprot - Q69ZS6
Ensembl - ENSMUSG00000051111
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sv2cENSDARG00000059997Danio rerio
 SV2CENSGALG00000014967Gallus gallus
 SV2CENSG00000122012Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Sv2a / Q9JIS5 / Synaptic vesicle glycoprotein 2A / Q7L0J3*ENSMUSG0000003848664
Sv2b / Q8BG39 / Synaptic vesicle glycoprotein 2B / Q7L1I2*ENSMUSG0000005302557
Svop / Q8BFT9 / Synaptic vesicle 2-related protein / Q8N4V2* / SV2 related protein*ENSMUSG0000004207817
Svopl / Q6PDF3 / Putative transporter SVOPL / Q8N434* / SVOP like*ENSMUSG0000002983017


Protein motifs (from Interpro)
Interpro ID Name
 IPR001646  Pentapeptide repeat
 IPR005828  Major facilitator, sugar transporter-like
 IPR005829  Sugar transporter, conserved site
 IPR011701  Major facilitator superfamily
 IPR020846  Major facilitator superfamily domain
 IPR022308  Synaptic vesicle protein SV2
 IPR036259  MFS transporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006836 neurotransmitter transport IEA
 biological_processGO:0007268 chemical synaptic transmission IEA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0008021 synaptic vesicle IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030672 synaptic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0005215 transporter activity IEA
 molecular_functionGO:0022857 transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001363 increased anxiety-related response "when compared to controls, subjects exhibit more responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:49752, J:53060]
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Allelic Composition: Npr2tm1Fgr/Npr2tm1Fgr
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
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Allelic Composition: Npr2tm1Fgr/Npr2tm1Fgr
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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