ENSMUSG00000051207


Mus musculus

Features
Gene ID: ENSMUSG00000051207
  
Biological name :Mrgprd
  
Synonyms : Mas-related G-protein coupled receptor member D / Mrgprd / Q91ZB8
  
Possible biological names infered from orthology : MAS related GPR family member D / Q8TDS7
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: F5
Gene start: 145314835
Gene end: 145324086
  
Corresponding Affymetrix probe sets: 10559389 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000063021
NCBI entrez gene - 211578     See in Manteia.
MGI - MGI:3033142
RefSeq - NM_203490
RefSeq Peptide - NP_987075
swissprot - Q5UCB4
swissprot - Q91ZB8
Ensembl - ENSMUSG00000051207
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MRGPRDENSG00000172938Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8CIP3 / Mrgprx1 / Mas-related G-protein coupled receptor member X1 ENSMUSG0000007055234
Q91ZB9 / Mrgprb5 / Mas-related G-protein coupled receptor member B5 ENSMUSG0000007055133
Q3UG50 / Mrgprx2 / Mas-related G-protein coupled receptor member X2 ENSMUSG0000007410933
Mrgpra9 / Q96LB2* / Q96LA9* / Q96LB0* / Q96LB1* / MRGPRX1* / MRGPRX2* / MRGPRX3* / MRGPRX4* / MAS related GPR family member X1* / MAS related GPR family member X3* / MAS related GPR family ...ENSMUSG0000007411133
Q3UG61 / Mrgprb1 / Mas-related G-protein coupled receptor member B1 ENSMUSG0000007054733
Mrgpra1 / Q96LB2* / Q96LA9* / Q96LB0* / Q96LB1* / MRGPRX1* / MRGPRX2* / MRGPRX3* / MRGPRX4* / MAS related GPR family member X1* / MAS related GPR family member X3* / MAS related GPR family ...ENSMUSG0000005065033
Q3KNA1 / Mrgprb2 / Mas-related G-protein coupled receptor member B2 ENSMUSG0000005042532
Mas1 / P30554 / Proto-onco Mas / P04201* / MAS1 proto-oncogene, G protein-coupled receptor*ENSMUSG0000006803732
Mrgpra3 / Q96LB2* / Q96LA9* / Q96LB0* / Q96LB1* / MRGPRX1* / MRGPRX2* / MRGPRX3* / MRGPRX4* / MAS related GPR family member X1* / MAS related GPR family member X3* / MAS related GPR family ...ENSMUSG0000007869832
Q91ZC0 / Mrgprb4 / Mas-related G-protein coupled receptor member B4 ENSMUSG0000007055031
Mrgpre / Q91ZB7 / Mas-related G-protein coupled receptor member E / Q86SM8* / MAS related GPR family member E*ENSMUSG0000004896531
Mrgprh / Q99MT8 / Mas-related G-protein coupled receptor member H ENSMUSG0000005940831
Mrgprf / Q8VCJ6 / Mas-related G-protein coupled receptor member F / Q96AM1* / MAS related GPR family member F*ENSMUSG0000003107030
Q91ZC1 / Mrgprb3 / Mas-related G-protein coupled receptor member B3 ENSMUSG0000007054630
Q91WW2 / Mrgpra4 / Mas-related G-protein coupled receptor member A4 / Q96LB2* / Q96LA9* / Q96LB0* / Q96LB1* / MRGPRX2* / MRGPRX3* / MRGPRX4* / MRGPRX1* / MAS related GPR family member X1* ...ENSMUSG0000006717330
Q91ZC6 / Mrgpra6 / Mus musculus MAS-related GPR, member A6 (Mrgpra6), transcript variant 1, mRNA. / Q96LB2* / Q96LA9* / Q96LB0* / Q96LB1* / MRGPRX3* / MRGPRX4* / MRGPRX1* / MRGPRX2* / MAS r...ENSMUSG0000005230329
Mrgpra2a / Q96LB2* / Q96LA9* / Q96LB0* / Q96LB1* / MRGPRX1* / MRGPRX2* / MRGPRX3* / MRGPRX4* / MAS related GPR family member X1* / MAS related GPR family member X3* / MAS related GPR family...ENSMUSG0000009397329
Mrgpra2b / Q96LB2* / Q96LA9* / Q96LB0* / Q96LB1* / MRGPRX1* / MRGPRX2* / MRGPRX3* / MRGPRX4* / MAS related GPR family member X1* / MAS related GPR family member X3* / MAS related GPR family...ENSMUSG0000009671929
Q7TN51 / Mrgprb8 / Mas-related G-protein coupled receptor member B8 ENSMUSG0000005087027
Mrgprg / Q91ZB5 / Mas-related G-protein coupled receptor member G / Q86SM5* / MAS related GPR family member G*ENSMUSG0000005027622


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR017452  GPCR, rhodopsin-like, 7TM
 IPR026232  Mas-related G protein-coupled receptor D
 IPR026234  Mas-related G protein-coupled receptor family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001973 increased thermal nociceptive threshold "a greater than average point at which thermal pain sensation is first detectable" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, J:17194]
Show

Allelic Composition: Dlg4tm2.1Grnt/Dlg4tm2.1Grnt
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Mrgprdtm1Mjz/Mrgprdtm1Mjz
Genetic Background: B6.129S1-Mrgprdtm1Mjz

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Itgb3tm1Hyn/Itgb3tm1Hyn,Itgb5tm1Des/Itgb5tm1Des
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

Allelic Composition: Mrgprdtm5Mjz/Mrgprdtm5Mjz
Genetic Background: involves: 129S1/Sv

 MP:0002736 abnormal nociception after inflammation "changes in pain thresholds after inflammation" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Glis3tm1Hiha/Glis3tm1Hiha
Genetic Background: involves: C57BL/6 * CBA

 MP:0002882 abnormal neuron "anomaly in the functional cells of the nervous system that receive, conduct, and transmit impulses " [MeSH:National Library of Medicine - Medical Subject Headings, 2003]
Show

Allelic Composition: Glis3tm1Hiha/Glis3tm1Hiha
Genetic Background: involves: C57BL/6 * CBA

 MP:0003463 abnormal single cell response "altered values from controls obtained upon extra- or intracellular recordings from single cells" [Nmice:Neuromice Consortium Submission]
Show

Allelic Composition: Mrgprdtm1.1(cre)And/Mrgprdtm1.1(cre)And
Genetic Background: B6.129S1-Mrgprdtm1.1(cre)And

Allelic Composition: Mrgprdtm1Mjz/Mrgprdtm1Mjz
Genetic Background: B6.129S1-Mrgprdtm1Mjz

 MP:0005498 hyporesponsive to tactile stimuli "reduced reflex action normally induced by touch or pain" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Glis3tm1Hiha/Glis3tm1Hiha
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Mrgprdtm1.1(cre)And/Mrgprdtm1.1(cre)And
Genetic Background: B6.129S1-Mrgprdtm1.1(cre)And

Allelic Composition: Mrgprdtm1Mjz/Mrgprdtm1Mjz
Genetic Background: B6.129S1-Mrgprdtm1Mjz

 MP:0008415 abnormal neurite morphology "any structural anomaly of a neuronal process, either a dendrite or an axon in vivo, or a filamentous projection from a neuron such as is seen in tissue culture" [PMID:12951572]
Show

Allelic Composition: Rettm1Ddg/Rettm1Ddg,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * C57BL/6J * CBA/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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