ENSMUSG00000051650


Mus musculus

Features
Gene ID: ENSMUSG00000051650
  
Biological name :B3gnt2
  
Synonyms : B3gnt2 / N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 / Q9Z222
  
Possible biological names infered from orthology : Q9NY97 / UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: A3.2
Gene start: 22834747
Gene end: 22860961
  
Corresponding Affymetrix probe sets: 10384656 (MoGene1.0st)   1420852_a_at (Mouse Genome 430 2.0 Array)   1450026_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000053528
Ensembl peptide - ENSMUSP00000060247
Ensembl peptide - ENSMUSP00000133306
NCBI entrez gene - 53625     See in Manteia.
MGI - MGI:1889505
RefSeq - NM_001169114
RefSeq - NM_016888
RefSeq Peptide - NP_001162585
RefSeq Peptide - NP_058584
swissprot - Q9Z222
swissprot - Q3TVJ9
swissprot - G3UWI7
Ensembl - ENSMUSG00000051650
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 b3gnt2aENSDARG00000052376Danio rerio
 b3gnt2bENSDARG00000091902Danio rerio
 B3GNT2ENSGALG00000008930Gallus gallus
 B3GNT2ENSG00000170340Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
B3gnt9 / Q8VI16 / UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 / Q6UX72*ENSMUSG0000006992035
B3gnt7 / Q8K0J2 / UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 / Q8NFL0*ENSMUSG0000007944534
B3gnt3 / Q5JCS9 / N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 / Q9Y2A9* / UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3*ENSMUSG0000003180334
B3gnt4 / Q1RLK6 / N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4 / Q9C0J1* / UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4*ENSMUSG0000002943133
B3gnt6 / Q3USF0 / Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase / Q6ZMB0* / UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6*ENSMUSG0000007400433
B3gnt8 / Q8R3I9 / UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 / Q7Z7M8*ENSMUSG0000005947932
O54904 / B3galt1 / Beta-1,3-galactosyltransferase 1 / Q9Y5Z6*ENSMUSG0000003478025
O54905 / B3galt2 / Beta-1,3-galactosyltransferase 2 / O43825*ENSMUSG0000003384924
Q9JI67 / B3galt5 / Mus musculus UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 (B3galt5), transcript variant 4, mRNA. / Q9Y2C3* / beta-1,3-galactosyltransferase 5*ENSMUSG0000007489223
Q9Z0F0 / B3galt4 / Beta-1,3-galactosyltransferase 4 / O96024*ENSMUSG0000006737022
B3gnt5 / Q8BGY6 / Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase / Q9BYG0* / UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5*ENSMUSG0000002268622
Q920V1 / B3galnt1 / UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 / O75752* / beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)*ENSMUSG0000004330021
Gm34653 / UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 10 (putative) / A8MXE2* / B3GNT10*ENSMUSG0000010716718


Protein motifs (from Interpro)
Interpro ID Name
 IPR002659  Glycosyl transferase, family 31


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0007411 axon guidance IMP
 biological_processGO:0007608 sensory perception of smell IMP
 biological_processGO:0030311 poly-N-acetyllactosamine biosynthetic process ISO
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEP
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0008378 galactosyltransferase activity IEA
 molecular_functionGO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity ISO
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA


Pathways (from Reactome)
Pathway description
Keratan sulfate biosynthesis
O-linked glycosylation of mucins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001003 abnormal olfactory receptor morphology "anomalous structure of the specialized proteins within the neurons of the olfactory epithelium that normally bind and detect odorants " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Drd2tm1Mok/Drd2tm1Mok
Genetic Background: involves: 129S/SvEv

 MP:0001364 decreased anxiety-related response "when compared to controls, subjects exhibit fewer responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:86626, J:85438, J:64043]
Show

Allelic Composition: Cacng4tm1Dgen/Cacng4tm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001984 abnormal olfaction "change in the ability to smell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Drd2tm1Mok/Drd2tm1Mok
Genetic Background: involves: 129S/SvEv

 MP:0002451 abnormal macrophage physiology "abnormal function or response of the phagocytic leukocytes involved in innate immunity, early non-adaptive phases of host-defense, antigen presentation, and which act as effector cells in humoral and cell-mediated immunity" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Sox10tm4Weg/Sox10+
Genetic Background: involves: 129P2/OlaHsd * C3H

 MP:0002573 behavioral despair "depression assayed by reduced escape attempts and/or immobility when placed in a stressful situation such as a forced swim test or a suspension test; or failure to seek pleasurable stimuli" [J:80395]
Show

Allelic Composition: Cacng4tm1Dgen/Cacng4tm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0003203 increased neuron apoptosis "increase in the number of neurons undergoing programmed cell death" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Drd2tm1Mok/Drd2tm1Mok
Genetic Background: involves: 129S/SvEv

 MP:0005348 increased T cell proliferation "increased clonal expansion of naive T cells in response to stimuli" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Sox10tm4Weg/Sox10+
Genetic Background: involves: 129P2/OlaHsd * C3H

 MP:0008560 increased tumor necrosis factor secretion "increase in the production or release of a serum glycoprotein produced by activated macrophages and NK cells and involved in initiating local inflammatory responses, particularly by its action on the endothelium of local blood vessels; its actions result in increased vascular permeability and induction of expression of adhesion molecules on the endothelium" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease", MESH:D12.644.276.374.500.800]
Show

Allelic Composition: Sox10tm4Weg/Sox10+
Genetic Background: involves: 129P2/OlaHsd * C3H

 MP:0008657 increased interleukin-1 beta secretion "increase in the production or release of an interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein on monocytes, macrophages and other cells; proteolytic processing of the precursor form by caspase 1 results in release of the active form of interleukin-1beta from the membrane" [MESH:D12.644.276.374.465.501.600]
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Allelic Composition: Sox10tm4Weg/Sox10+
Genetic Background: involves: 129P2/OlaHsd * C3H

 MP:0008705 increased interleukin-6 secretion "increase in the production or release of a cytokine that stimulates the growth and differentiation of B-cells and is also a growth factor for hybridomas and plasmacytomas, and is produced by many different cells including T-cells, monocytes and fibroblasts" [MESH:D12.644.276.374.465.506]
Show

Allelic Composition: Sox10tm4Weg/Sox10+
Genetic Background: involves: 129P2/OlaHsd * C3H

 MP:0008789 abnormal olfactory epithelium morphology "any structural anomaly in the epithelial cells that line the interior of the nose" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Drd2tm1Mok/Drd2tm1Mok
Genetic Background: involves: 129S/SvEv

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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