ENSMUSG00000051864


Mus musculus

Features
Gene ID: ENSMUSG00000051864
  
Biological name :Tbc1d22a
  
Synonyms : Q8R5A6 / Tbc1d22a / TBC1 domain family member 22A
  
Possible biological names infered from orthology : Q8WUA7
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: E2
Gene start: 86214459
Gene end: 86498503
  
Corresponding Affymetrix probe sets: 10426065 (MoGene1.0st)   1423776_s_at (Mouse Genome 430 2.0 Array)   1451107_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000065721
Ensembl peptide - ENSMUSP00000155727
NCBI entrez gene - 223754     See in Manteia.
MGI - MGI:1289265
RefSeq - XM_017316576
RefSeq - NM_145476
RefSeq - XM_006520833
RefSeq Peptide - NP_663451
swissprot - Q8R5A6
Ensembl - ENSMUSG00000051864
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tbc1d22aENSDARG00000045510Danio rerio
 TBC1D22AENSGALG00000043058Gallus gallus
 Q8WUA7ENSG00000054611Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tbc1d22b / TBC1 domain family, member 22B / Q9NU19*ENSMUSG0000004220360
Tbck / TBC1 domain containing kinase / Q8TEA7*ENSMUSG0000002803021


Protein motifs (from Interpro)
Interpro ID Name
 IPR000195  Rab-GTPase-TBC domain
 IPR035969  Rab-GTPase-TBC domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0031338 regulation of vesicle fusion IBA
 biological_processGO:0090630 activation of GTPase activity IBA
 cellular_componentGO:0005622 intracellular IBA
 cellular_componentGO:0012505 endomembrane system IBA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0017137 Rab GTPase binding IBA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0071889 14-3-3 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0010169 decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number "a reduction in the number of the CD4-positive, CD25-positive T cell subset which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release" [ISBN:0781735149]
Show

Allelic Composition: Spata22tm1b(KOMP)Wtsi/Spata22tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Spata22tm1b(KOMP)Wtsi/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr