ENSMUSG00000052539


Mus musculus

Features
Gene ID: ENSMUSG00000052539
  
Biological name :Magi3
  
Synonyms : Magi3 / Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 / Q9EQJ9
  
Possible biological names infered from orthology : membrane associated guanylate kinase, WW and PDZ domain containing 3 / Q5TCQ9
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: F2.2
Gene start: 104013259
Gene end: 104220374
  
Corresponding Affymetrix probe sets: 10500847 (MoGene1.0st)   1421035_a_at (Mouse Genome 430 2.0 Array)   1435461_at (Mouse Genome 430 2.0 Array)   1450101_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000067932
Ensembl peptide - ENSMUSP00000112934
Ensembl peptide - ENSMUSP00000113713
NCBI entrez gene - 99470     See in Manteia.
MGI - MGI:1923484
RefSeq - NM_001159354
RefSeq - NM_133853
RefSeq Peptide - NP_001152826
RefSeq Peptide - NP_598614
swissprot - G5E8T6
swissprot - Q9EQJ9
Ensembl - ENSMUSG00000052539
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 magi3aENSDARG00000101869Danio rerio
 magi3bENSDARG00000025974Danio rerio
 MAGI3ENSGALG00000001816Gallus gallus
 MAGI3ENSG00000081026Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Magi2 / Q9WVQ1 / Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 / Q86UL8* / membrane associated guanylate kinase, WW and PDZ domain containing 2*ENSMUSG0000004000340
Magi1 / Q6RHR9 / Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 / Q96QZ7* / membrane associated guanylate kinase, WW and PDZ domain containing 1*ENSMUSG0000004509538
1 / Sav1 / Q8VEB2 / Q9H4B6* / salvador family WW domain containing protein 1*ENSMUSG000000210677
Magix / Q4KL35 / PDZ domain-containing protein MAGIX / MAGI family member, X-linked*ENSMUSG000000311476


Protein motifs (from Interpro)
Interpro ID Name
 IPR001202  WW domain
 IPR001478  PDZ domain
 IPR008144  Guanylate kinase-like domain
 IPR008145  Guanylate kinase/L-type calcium channel beta subunit
 IPR020590  Guanylate kinase, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030035  Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3
 IPR036020  WW domain superfamily
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0043507 positive regulation of JUN kinase activity IGI
 biological_processGO:0046328 regulation of JNK cascade IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005911 cell-cell junction IDA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005109 frizzled binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0032947 protein-containing complex scaffold activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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