ENSMUSG00000052833


Mus musculus

Features
Gene ID: ENSMUSG00000052833
  
Biological name :Sae1
  
Synonyms : Q9R1T2 / Sae1 / SUMO-activating enzyme subunit 1 SUMO-activating enzyme subunit 1, N-terminally processed
  
Possible biological names infered from orthology : Q9UBE0 / SUMO1 activating enzyme subunit 1
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: A2
Gene start: 16320234
Gene end: 16387806
  
Corresponding Affymetrix probe sets: 10560260 (MoGene1.0st)   1416443_a_at (Mouse Genome 430 2.0 Array)   1430021_a_at (Mouse Genome 430 2.0 Array)   1430022_at (Mouse Genome 430 2.0 Array)   1440185_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000092409
Ensembl peptide - ENSMUSP00000147409
Ensembl peptide - ENSMUSP00000147771
NCBI entrez gene - 56459     See in Manteia.
MGI - MGI:1929264
RefSeq - XM_011250653
RefSeq - NM_001285891
RefSeq - NM_001285892
RefSeq - NM_019748
RefSeq Peptide - NP_001272821
RefSeq Peptide - NP_062722
RefSeq Peptide - NP_001272820
swissprot - Q9R1T2
Ensembl - ENSMUSG00000052833
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sae1ENSDARG00000010487Danio rerio
 SAE1ENSG00000142230Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000011  Ubiquitin/SUMO-activating enzyme E1
 IPR000594  THIF-type NAD/FAD binding fold
 IPR035985  Ubiquitin-activating enzyme


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006464 cellular protein modification process IEA
 biological_processGO:0016925 protein sumoylation ISO
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0031510 SUMO activating enzyme complex IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0008641 ubiquitin-like modifier activating enzyme activity IEA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0019948 SUMO activating enzyme activity IEA
 molecular_functionGO:0043008 ATP-dependent protein binding IEA
 molecular_functionGO:0044388 small protein activating enzyme binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
SUMO is conjugated to E1 (UBA2:SAE1)
SUMO is transferred from E1 to E2 (UBE2I, UBC9)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000015120 Ube2i / P63280 / ubiquitin-conjugating enzyme E2I / P63279*  / reaction
 ENSMUSG00000052997 Uba2 / Q9Z1F9 / ubiquitin-like modifier activating enzyme 2 / Q9UBT2*  / complex
 ENSMUSG00000026021 Sumo1 / P63166 / Small ubiquitin-related modifier 1 / P63165* / small ubiquitin-like modifier 1*  / complex / reaction






 

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