ENSMUSG00000053289


Mus musculus

Features
Gene ID: ENSMUSG00000053289
  
Biological name :Ddx10
  
Synonyms : Ddx10 / Probable ATP-dependent RNA helicase DDX10 / Q80Y44
  
Possible biological names infered from orthology : DEAD-box helicase 10 / Q13206
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: A5.3
Gene start: 53098635
Gene end: 53248053
  
Corresponding Affymetrix probe sets: 10593508 (MoGene1.0st)   1428563_at (Mouse Genome 430 2.0 Array)   1452838_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000065198
NCBI entrez gene - 77591     See in Manteia.
MGI - MGI:1924841
RefSeq - NM_029936
RefSeq Peptide - NP_084212
swissprot - Q80Y44
Ensembl - ENSMUSG00000053289
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ddx10ENSDARG00000061865Danio rerio
 DDX10ENSGALG00000017156Gallus gallus
 DDX10ENSG00000178105Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000629  ATP-dependent RNA helicase DEAD-box, conserved site
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR025313  Domain of unknown function DUF4217
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010501 RNA secondary structure unwinding IBA
 biological_processGO:0097065 anterior head development IMP
 cellular_componentGO:0005730 nucleolus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000111 cleft palate "congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
Show

Allelic Composition: Tbptm1.1Xjl/Tbp+
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0000445 short snout "reduced length of the anterior facial part of the muzzle" [J:53370]
Show

Allelic Composition: Tbptm1.1Xjl/Tbp+
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Tbptm1.1Xjl/Tbp+
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Tbptm1.1Xjl/Tbp+
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0003961 decreased lean body mass "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
Show

Allelic Composition: Tbptm1.1Xjl/Tbp+
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0010124 decreased bone mineral content "reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tbptm1.1Xjl/Tbp+
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0011862 decreased cranium length "having an decreased dorsal-to-ventral distance of the cranium" [MGI:mnk]
Show

Allelic Composition: Tbptm1.1Xjl/Tbp+
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0013618 decreased areal bone mineral density "reduction of the mineral mass per unit area of bone, the hard, rigid form of connective tissue constituting most of the skeleton of vertebrates and composed chiefly of calcium salts; expressed as the amount of mineral per area cm^2 of bone (usually in g/cm^2), with results generated from Dual-energy X-ray absorptiometry (DXA or DEXA) tests" [PMID:12730800, PMID:17481978]
Show

Allelic Composition: Tbptm1.1Xjl/Tbp+
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr