ENSMUSG00000053886


Mus musculus

Features
Gene ID: ENSMUSG00000053886
  
Biological name :Sh2d4a
  
Synonyms : Q9D7V1 / Sh2d4a / SH2 domain-containing protein 4A
  
Possible biological names infered from orthology : Q9H788 / SH2 domain containing 4A
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: B3.3
Gene start: 68276567
Gene end: 68347699
  
Corresponding Affymetrix probe sets: 10572097 (MoGene1.0st)   1453377_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000148702
Ensembl peptide - ENSMUSP00000070825
NCBI entrez gene - 72281     See in Manteia.
MGI - MGI:1919531
RefSeq - NM_028182
RefSeq - XM_006509751
RefSeq Peptide - NP_082458
swissprot - A0A1D5RMA9
swissprot - Q9D7V1
Ensembl - ENSMUSG00000053886
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SH2D4AENSGALG00000010122Gallus gallus
 Q9H788ENSG00000104611Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A6X942 / Sh2d4b / SH2 domain-containing protein 4B / Q5SQS7* / SH2 domain containing 4B*ENSMUSG0000003783341
Q9QXK9 / Sh2d2a / SH2 domain containing 2A / Q9NP31*ENSMUSG0000002807113
Hsh2d / Q6VYH9 / Hematopoietic SH2 domain-containing protein / Q96JZ2* / hematopoietic SH2 domain containing*ENSMUSG0000006200711
Sh2d7 / Q8BI17 / SH2 domain-containing protein 7 ENSMUSG000000464600


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR036860  SH2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010923 negative regulation of phosphatase activity IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0019902 phosphatase binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Notch1tm1Agt/Notch1tm1Agt,Notch2tm1Frad/Notch2tm1Frad,Ptf1atm1(cre)Hnak/Ptf1a+
Genetic Background: involves: 129 * BALB/cJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr