ENSMUSG00000054414


Mus musculus

Features
Gene ID: ENSMUSG00000054414
  
Biological name :Slc30a7
  
Synonyms : Q9JKN1 / Slc30a7 / Zinc transporter 7
  
Possible biological names infered from orthology : Q8NEW0 / solute carrier family 30 member 7
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: G1
Gene start: 115938973
Gene end: 116007406
  
Corresponding Affymetrix probe sets: 10501593 (MoGene1.0st)   1435717_at (Mouse Genome 430 2.0 Array)   1450697_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000065254
NCBI entrez gene - 66500     See in Manteia.
MGI - MGI:1913750
RefSeq - NM_023214
RefSeq - XM_017319686
RefSeq Peptide - NP_075703
swissprot - Q9JKN1
Ensembl - ENSMUSG00000054414
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 A5PMX1ENSDARG00000019998Danio rerio
 SLC30A7ENSGALG00000020879Gallus gallus
 Q8NEW0ENSG00000162695Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8R4H9 / Slc30a5 / Zinc transporter 5 / Q8TAD4* / solute carrier family 30 member 5*ENSMUSG0000002162939
Q8BJM5 / Slc30a6 / Zinc transporter 6 / Q6NXT4* / solute carrier family 30 member 6*ENSMUSG0000002406921


Protein motifs (from Interpro)
Interpro ID Name
 IPR002524  Cation efflux protein
 IPR027469  Cation efflux transmembrane domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006812 cation transport IEA
 biological_processGO:0006829 zinc ion transport IEA
 biological_processGO:0010043 response to zinc ion IBA
 biological_processGO:0032119 sequestering of zinc ion IEP
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0061088 regulation of sequestering of zinc ion IBA
 biological_processGO:0071577 zinc ion transmembrane transport IEA
 biological_processGO:0098655 cation transmembrane transport IEA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0016020 membrane IBA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IDA
 cellular_componentGO:0031982 vesicle IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0005385 zinc ion transmembrane transporter activity TAS
 molecular_functionGO:0008270 zinc ion binding IC
 molecular_functionGO:0008324 cation transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001670 abnormal mineral absorption "anomalous ability of the body to take in any inorganic substance that has importance in body functions" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ets2tm3Rgo/Ets2tm3Rgo,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ

 MP:0005459 decreased percent body fat "less fat, relative to the norm, as a percentage of total body weight" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ets2tm3Rgo/Ets2tm3Rgo,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ

 MP:0006357 abnormal circulating mineral level "anomalous concentration in the blood of any naturally occurring, homogeneous inorganic solid substance having a definite chemical composition and highly ordered atomic arrangement that is required for growth and survival" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ets2tm3Rgo/Ets2tm3Rgo,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ

 MP:0008489 postnatal slow weight gain "the weight gain over a span of postnatal developmental time is slower than controls, with or without ever attaining a similar weight to controls as adults" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ets2tm3Rgo/Ets2tm3Rgo,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ

 MP:0009615 abnormal zinc homeostasis "anomaly in the processes involved in the maintenance of an internal equilibrium of zinc that normally is a cofactor in many proteins" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ets2tm3Rgo/Ets2tm3Rgo,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ

 MP:0011940 decreased food intake "reduction in the total number of calories/food amount taken in over time when compared to the normal state" [MGI:csmith]
Show

Allelic Composition: Ets2tm3Rgo/Ets2tm3Rgo,Meox2tm1(cre)Sor/Meox2+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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