ENSMUSG00000054733


Mus musculus

Features
Gene ID: ENSMUSG00000054733
  
Biological name :Msra
  
Synonyms : Mitochondrial peptide methionine sulfoxide reductase / Msra / Q9D6Y7
  
Possible biological names infered from orthology : methionine sulfoxide reductase A / Q9UJ68
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: D1
Gene start: 64122625
Gene end: 64455903
  
Corresponding Affymetrix probe sets: 10420811 (MoGene1.0st)   1448856_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000065754
Ensembl peptide - ENSMUSP00000147689
Ensembl peptide - ENSMUSP00000148189
NCBI entrez gene - 110265     See in Manteia.
MGI - MGI:106916
RefSeq - NM_026322
RefSeq - XM_011244921
RefSeq - NM_001253712
RefSeq - NM_001253714
RefSeq - NM_001253715
RefSeq - NM_001253716
RefSeq - XM_006518429
RefSeq Peptide - NP_001240641
RefSeq Peptide - NP_001240644
RefSeq Peptide - NP_001240645
RefSeq Peptide - NP_001334568
RefSeq Peptide - NP_080598
RefSeq Peptide - NP_001240643
swissprot - A0A1B0GT40
swissprot - Q9D6Y7
Ensembl - ENSMUSG00000054733
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 msraENSDARG00000029587Danio rerio
 MSRAENSGALG00000028032Gallus gallus
 MSRAENSG00000175806Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002569  Peptide methionine sulphoxide reductase MsrA
 IPR036509  Peptide methionine sulphoxide reductase MsrA superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0015629 actin cytoskeleton ISO
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0008113 peptide-methionine (S)-S-oxide reductase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
Protein repair


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Rhotm4.1(RHO*/EGFP)Jhw/Rho+
Genetic Background: B6.129S7-Rhotm4.1(RHO*/EGFP)Jhw

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
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Allelic Composition: Tnfsf4Ath1-PERA/EiJ/Tnfsf4Ath1-PERA/EiJ
Genetic Background: B6.PERA-Tnfsf4Ath1-PERA/EiJ/Pgn

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Rhotm4.1(RHO*/EGFP)Jhw/Rho+
Genetic Background: B6.129S7-Rhotm4.1(RHO*/EGFP)Jhw

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Tnfsf4Ath1-PERA/EiJ/Tnfsf4Ath1-PERA/EiJ
Genetic Background: B6.PERA-Tnfsf4Ath1-PERA/EiJ/Pgn

 MP:0003674 oxidative stress "condition characterized by an accumulation of free radical groups in the body, which creates a potentially unstable and damaging cellular environment linked to tissue damage, accelerated aging, and degenerative disease; can result from many factors, including exposure to alcohol, medications, poor nutrition, trauma, cold or toxins; may be indicated by low antioxidant levels measured in blood plasma" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Tnfsf4Ath1-PERA/EiJ/Tnfsf4Ath1-PERA/EiJ
Genetic Background: B6.PERA-Tnfsf4Ath1-PERA/EiJ/Pgn

 MP:0005319 abnormal enzyme/ coenzyme level "altered concentration of any of these proteins, or their cofactors, that act as catalysts to induce chemical changes in other substances" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tnfsf4Ath1-PERA/EiJ/Tnfsf4Ath1-PERA/EiJ
Genetic Background: B6.PERA-Tnfsf4Ath1-PERA/EiJ/Pgn

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000028367 Txn1 / P10639 / thioredoxin 1 / TXN* / P10599* / thioredoxin*  / reaction






 

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