ENSMUSG00000056436


Mus musculus

Features
Gene ID: ENSMUSG00000056436
  
Biological name :Cyct
  
Synonyms : Cyct / Cytochrome c, testis-specific / P00015
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: C3
Gene start: 76353942
Gene end: 76360450
  
Corresponding Affymetrix probe sets: 10483851 (MoGene1.0st)   1450752_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000028430
NCBI entrez gene - 13067     See in Manteia.
MGI - MGI:88579
RefSeq - NM_009989
RefSeq - XM_011239273
RefSeq Peptide - NP_034119
swissprot - P00015
Ensembl - ENSMUSG00000056436
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cycsbENSDARG00000044562Danio rerio
 ENSGALG00000040718Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cycs / P62897 / Cytochrome c, somatic ENSMUSG0000006369487
P62897 / Gm10053 / predicted gene 10053ENSMUSG0000005892787


Protein motifs (from Interpro)
Interpro ID Name
 IPR002327  Cytochrome c, class IA/ IB
 IPR009056  Cytochrome c-like domain
 IPR036909  Cytochrome c-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c IBA
 biological_processGO:0006123 mitochondrial electron transport, cytochrome c to oxygen IBA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0042743 hydrogen peroxide metabolic process IDA
 biological_processGO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:2001244 positive regulation of intrinsic apoptotic signaling pathway IDA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005758 mitochondrial intermembrane space IBA
 cellular_componentGO:0070469 respiratory chain IEA
 molecular_functionGO:0009055 electron transfer activity IEA
 molecular_functionGO:0020037 heme binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000242 impaired fertilization "defect or reduced ability in the process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronucei" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: H2afxtm1Nus/H2afx+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
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Allelic Composition: H2afxtm1Nus/H2afx+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0002216 abnormal seminiferous tubule morphology "malformation of the tubules in the testes where spermatogenesis occurs" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: H2afxtm1Nus/H2afx+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0002674 abnormal sperm motility "anomalies in the mobility of the spermatozoa" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: H2afxtm1Nus/H2afx+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0002687 oligozoospermia "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312]
Show

Allelic Composition: H2afxtm1Nus/H2afx+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0003205 testicular atrophy "wasting of the male reproductive glands resulting in reduced size" [RGD:Rat Genome Database submission]
Show

Allelic Composition: H2afxtm1Nus/H2afx+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0010959 abnormal oxidative phosphorylation "any anomaly in the process of phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain; oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis" [GO:0006119]
Show

Allelic Composition: H2afxtm1Nus/H2afx+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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