ENSMUSG00000056598


Mus musculus

Features
Gene ID: ENSMUSG00000056598
  
Biological name :Drc3
  
Synonyms : Drc3 / Dynein regulatory complex subunit 3 / Q9D5E4
  
Possible biological names infered from orthology : Q9H069
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B2
Gene start: 60353329
Gene end: 60394341
  
Corresponding Affymetrix probe sets: 10376579 (MoGene1.0st)   1424340_at (Mouse Genome 430 2.0 Array)   1440117_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000065525
Ensembl peptide - ENSMUSP00000091691
Ensembl peptide - ENSMUSP00000104362
Ensembl peptide - ENSMUSP00000104363
NCBI entrez gene - 74665     See in Manteia.
MGI - MGI:1921915
RefSeq - NM_029044
RefSeq - XM_006534382
RefSeq Peptide - NP_083320
swissprot - Q9D5E4
swissprot - Q5SX99
swissprot - F6Q537
swissprot - Q8BWX4
Ensembl - ENSMUSG00000056598
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 drc3ENSDARG00000041300Danio rerio
 DRC3ENSGALG00000004916Gallus gallus
 DRC3ENSG00000171962Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Lrrc9 / Q8CDN9 / Leucine-rich repeat-containing protein 9 / Q6ZRR7* / leucine rich repeat containing 9*ENSMUSG0000002109022
Lrguk / Q9D5S7 / Leucine-rich repeat and guanylate kinase domain-containing protein / Q96M69* / leucine rich repeats and guanylate kinase domain containing*ENSMUSG0000005621520
Dnaaf1 / Q9D2H9 / Dynein assembly factor 1, axonemal / Q8NEP3* / dynein axonemal assembly factor 1*ENSMUSG0000003183117
Lrrc49 / leucine rich repeat containing 49 / Q8IUZ0*ENSMUSG0000004776614
Ppp1r7 / Q3UM45 / Protein phosphatase 1 regulatory subunit 7 / Q15435*ENSMUSG0000002627512
Lrrc23 / O35125 / Leucine-rich repeat-containing protein 23 / Q53EV4* / leucine rich repeat containing 23*ENSMUSG000000301258


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005930 axoneme IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000440 domed skull 
Show

Allelic Composition: Drc3m6Bei/Drc3m6Bei,Rgs4tm1Dgen/Rgs4+
Genetic Background: involves: 129P2/OlaHsd * A/J * C57BL/6

 MP:0000807 abnormal hippocampus morphology "absent or malformed deep lying structure of the cerebrum involved with memory storage and spatial navigation" [The Atlas of Mouse Development:ISBN 0-12-402035-6, MGI:Cls, J:38857]
Show

Allelic Composition: Drc3m6Bei/Drc3m6Bei,Rgs4tm1Dgen/Rgs4+
Genetic Background: involves: 129P2/OlaHsd * A/J * C57BL/6

 MP:0006254 thin cerebral cortex "decreased depth of the mantle covering the surface of the cerebral hemispheres" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:84683]
Show

Allelic Composition: Drc3m6Bei/Drc3m6Bei,Rgs4tm1Dgen/Rgs4+
Genetic Background: involves: 129P2/OlaHsd * A/J * C57BL/6

 MP:0008283 small hippocampus "reduced size of the deep lying structure of the cerebrum involved with memory storage and spatial navigation" [ISBN:0-12-402035-6 "Kaufman, MH The Atlas of Mouse Development", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Drc3m6Bei/Drc3m6Bei,Rgs4tm1Dgen/Rgs4+
Genetic Background: involves: 129P2/OlaHsd * A/J * C57BL/6

 MP:0008535 enlarged lateral ventricles "increased size of the cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube; they are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle" [MESH:A08.186.211.276.650, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Drc3m6Bei/Drc3m6Bei,Rgs4tm1Dgen/Rgs4+
Genetic Background: involves: 129P2/OlaHsd * A/J * C57BL/6

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Drc3m6Bei/Drc3m6Bei,Rgs4tm1Dgen/Rgs4+
Genetic Background: involves: 129P2/OlaHsd * A/J * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr