ENSMUSG00000056978


Mus musculus

Features
Gene ID: ENSMUSG00000056978
  
Biological name :Hamp2
  
Synonyms : Hamp2 / Hepcidin-2 / Q80T19
  
Possible biological names infered from orthology : HAMP / hepcidin antimicrobial peptide / P81172
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: B1
Gene start: 30922372
Gene end: 30924681
  
Corresponding Affymetrix probe sets: 10562166 (MoGene1.0st)   1436643_x_at (Mouse Genome 430 2.0 Array)   1456289_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000151677
Ensembl peptide - ENSMUSP00000074240
Ensembl peptide - ENSMUSP00000145962
NCBI entrez gene - 66438     See in Manteia.
MGI - MGI:2153530
RefSeq - NM_183257
RefSeq Peptide - NP_899080
swissprot - Q80T19
swissprot - A0A0U1RPF4
swissprot - F6VHS4
swissprot - Q5M9M1
Ensembl - ENSMUSG00000056978
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HAMPENSG00000105697Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Hamp / Q9EQ21 / Hepcidin / P81172* / hepcidin antimicrobial peptide*ENSMUSG0000005044088


Protein motifs (from Interpro)
Interpro ID Name
 IPR010500  Hepcidin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006879 cellular iron ion homeostasis IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0031640 killing of cells of other organism IEA
 biological_processGO:0034760 negative regulation of iron ion transmembrane transport IBA
 biological_processGO:0042742 defense response to bacterium IEA
 biological_processGO:0050832 defense response to fungus IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005623 cell IEA
 molecular_functionGO:0005179 hormone activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0008810 increased circulating iron level "elevation in the concentration of iron in the blood" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Hamp/Hamp2tm1.1(HAMP)Bjs/Hamp/Hamp2tm1.1(HAMP)Bjs
Genetic Background: involves: 129 * NTac:NIHBS

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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