ENSMUSG00000058579


Mus musculus

Features
Gene ID: ENSMUSG00000058579
  
Biological name :Cela2a
  
Synonyms : Cela2a / Chymotrypsin-like elastase family member 2A / P05208
  
Possible biological names infered from orthology : CELA2B / chymotrypsin like elastase family member 2B / P08217 / P08218
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: E1
Gene start: 141814962
Gene end: 141826160
  
Corresponding Affymetrix probe sets: 10518050 (MoGene1.0st)   1448281_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000099539
NCBI entrez gene - 13706     See in Manteia.
MGI - MGI:95316
RefSeq - NM_007919
RefSeq Peptide - NP_031945
swissprot - P05208
Ensembl - ENSMUSG00000058579
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ela2ENSDARG00000056744Danio rerio
 ela2lENSDARG00000056765Danio rerio
 CELA2AENSGALG00000004568Gallus gallus
 CELA2AENSG00000142615Homo sapiens
 CELA2BENSG00000215704Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cela3b / Q9CQ52 / Chymotrypsin-like elastase family member 3B / P08861* / P09093* / CELA3A* / chymotrypsin like elastase family member 3A*ENSMUSG0000002343355
Cela1 / Q91X79 / Chymotrypsin-like elastase family member 1 / Q9UNI1*ENSMUSG0000002303153
Ctrc / chymotrypsin-C / Q99895*ENSMUSG0000006247853
Cela3a / chymotrypsin-like elastase family, member 3A / P09093* / CELA3B* / P08861* / chymotrypsin like elastase family member 3B*ENSMUSG0000007852052
Ctrb1 / Q9CR35 / Chymotrypsinogen B Chymotrypsin B chain A Chymotrypsin B chain B Chymotrypsin B chain C / CTRB2* / P17538* / Q6GPI1* / chymotrypsinogen B1* / chymotrypsinogen B2*ENSMUSG0000003195738
Ctrl / chymotrypsin-like / P40313*ENSMUSG0000003189638
Ovch2 / Q7M761 / Ovochymase-2 / ovochymase 2 (gene/pseudogene)*ENSMUSG0000004823631


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IMP
 biological_processGO:0061436 establishment of skin barrier IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0036457 keratohyalin granule ISO
 molecular_functionGO:0004252 serine-type endopeptidase activity IBA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0017171 serine hydrolase activity ISO


Pathways (from Reactome)
Pathway description
Formation of the cornified envelope


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000074155 Klk5 / kallikrein related-peptidase 5 / Q9Y337*  / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr