ENSMUSG00000058594


Mus musculus

Features
Gene ID: ENSMUSG00000058594
  
Biological name :Fbxo18
  
Synonyms : Fbxo18 / Mus musculus F-box protein 18 (Fbxo18), transcript variant 5, mRNA. / Q8K2I9
  
Possible biological names infered from orthology : F-box protein, helicase, 18 / Q8NFZ0
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: A1
Gene start: 11742573
Gene end: 11777582
  
Corresponding Affymetrix probe sets: 10480064 (MoGene1.0st)   1452153_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000071495
Ensembl peptide - ENSMUSP00000116392
NCBI entrez gene - 50755     See in Manteia.
MGI - MGI:1354699
RefSeq - XM_006497509
RefSeq - NM_001348235
RefSeq - NM_001348237
RefSeq - NM_015792
RefSeq - XM_006497505
RefSeq - XM_006497506
RefSeq - XM_006497507
RefSeq - XM_006497508
RefSeq Peptide - NP_001335164
RefSeq Peptide - NP_001335166
RefSeq Peptide - NP_056607
swissprot - A2AS52
swissprot - Q8K2I9
Ensembl - ENSMUSG00000058594
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fbxo18ENSDARG00000062983Danio rerio
 F1ND48ENSGALG00000008162Gallus gallus
 FBXO18ENSG00000134452Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000212  DNA helicase, UvrD/REP type
 IPR001810  F-box domain
 IPR014017  UvrD-like DNA helicase, C-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR036047  F-box-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000724 double-strand break repair via homologous recombination ISS
 biological_processGO:0000737 DNA catabolic process, endonucleolytic IEA
 biological_processGO:0001934 positive regulation of protein phosphorylation IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus ISO
 biological_processGO:0008219 cell death IEA
 biological_processGO:0016567 protein ubiquitination ISO
 biological_processGO:0031297 replication fork processing IEA
 biological_processGO:0032508 DNA duplex unwinding IEA
 biological_processGO:0035562 negative regulation of chromatin binding IMP
 biological_processGO:0048478 replication fork protection IMP
 biological_processGO:0072429 response to intra-S DNA damage checkpoint signaling IEA
 biological_processGO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage IEA
 biological_processGO:2000042 negative regulation of double-strand break repair via homologous recombination IEA
 cellular_componentGO:0000785 chromatin IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0019005 SCF ubiquitin ligase complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003678 DNA helicase activity IEA
 molecular_functionGO:0003690 double-stranded DNA binding IEA
 molecular_functionGO:0003697 single-stranded DNA binding IEA
 molecular_functionGO:0004003 ATP-dependent DNA helicase activity IEA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0015616 DNA translocase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0043138 3"-5" DNA helicase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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