| MP:0000496 | abnormal small intestine morphology | "structural or developmental anomalies of the intestinum tenue " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Gt(ROSA)26Sortm1(cre/ERT)Brn/Gt(ROSA)26Sor+,Lin9tm1.1Sgau/Lin9tm1.1Sgau
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * SJL
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| MP:0001260 | increased body weight | "greater than normal average weight " [J:33400] |
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Allelic Composition: Cdk4tm1Kiyo/Cdk4tm1Kiyo
Genetic Background: involves: 129S1/Sv
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| MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: Slc26a4pdsm/Slc26a4pdsm
Genetic Background: BXA7/PgnJ-Slc26a4pdsm/J
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| MP:0001672 | abnormal embryogenesis/ development | "anomaly in the establishment of the characteristic configuration of the embryonic body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ctcfltm1.1Vloc/Ctcfltm1.1Vloc
Genetic Background: involves: 129S1/Sv * C57BL/6 * SJL
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| MP:0001925 | male infertility | "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
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Allelic Composition: Cdk4tm1Kiyo/Cdk4tm1Kiyo,Lin9tm1Orc/Lin9tm1Orc
Genetic Background: involves: 129S1/Sv
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| MP:0001926 | female infertility | "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193] |
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Allelic Composition: Cdk4tm1Kiyo/Cdk4tm1Kiyo,Lin9tm1Orc/Lin9tm1Orc
Genetic Background: involves: 129S1/Sv
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| MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Gt(ROSA)26Sortm1(cre/ERT)Brn/Gt(ROSA)26Sor+,Lin9tm1.1Sgau/Lin9tm1.1Sgau
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * SJL
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| MP:0003077 | abnormal cell cycle | "failure to progress or abnormal progression through the stages of of the cell cycle" [smb:Susan M. Bello, Mouse Genome Informatics Curator, J:91266] |
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Allelic Composition: Cdk4tm1Kiyo/Cdk4tm1Kiyo,Lin9tm1Orc/Lin9tm1Orc
Genetic Background: involves: 129S1/Sv
Allelic Composition: Cdk4tm1Kiyo/Cdk4+,Lin9tm1Orc/Lin9+
Genetic Background: involves: 129S1/Sv
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| MP:0003087 | absent allantois | "missing fetal membrane which contributes to the formation of the umbilical cord and placenta" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Ctcfltm1.1Vloc/Ctcfltm1.1Vloc
Genetic Background: involves: 129S1/Sv * C57BL/6 * SJL
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| MP:0003111 | abnormal nucleus morphology | "abnormalities in the nucleus and/or its surrounding membrane" [J:91473, smb:Susan M. Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Gt(ROSA)26Sortm1(cre/ERT)Brn/Gt(ROSA)26Sor+,Lin9tm1.1Sgau/Lin9tm1.1Sgau
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * SJL
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| MP:0004046 | abnormal mitosis | "anomaly in the process of cell division including both division of the nucleus (karyokinesis) and the cytoplasm (cytokinesis) " [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Gt(ROSA)26Sortm1(cre/ERT)Brn/Gt(ROSA)26Sor+,Lin9tm1.1Sgau/Lin9tm1.1Sgau
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * SJL
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| MP:0004804 | decreased susceptibility to autoimmune diabetes | "reduced likelihood that an organism will develop inflammatory pancreatic disease resulting from the body attacking and destroying the insulin-producing beta islet cells of the pancreas" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cdk4tm1Kiyo/Cdk4+,Lin9tm1Orc/Lin9+
Genetic Background: involves: 129S1/Sv
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| MP:0004965 | inner cell mass degeneration | |
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Allelic Composition: Ctcfltm1.1Vloc/Ctcfltm1.1Vloc
Genetic Background: involves: 129S1/Sv * C57BL/6 * SJL
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| MP:0005030 | absent amnion | "missing innermost of the extraembryonic membranes" [dlb:Donna Burkart , Mouse Genome Informatics Curator, J:57761] |
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Allelic Composition: Ctcfltm1.1Vloc/Ctcfltm1.1Vloc
Genetic Background: involves: 129S1/Sv * C57BL/6 * SJL
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| MP:0008108 | abnormal small intestinal villus morphology | "any structural anomaly of the tiny hair-like projections that protrude from the inside of the small intestine that contain blood vessels that capture digested nutrients that are absorbed through the intestinal wall; the villi increase the absorptive surface area of the small intestine by approximately 30-fold" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gt(ROSA)26Sortm1(cre/ERT)Brn/Gt(ROSA)26Sor+,Lin9tm1.1Sgau/Lin9tm1.1Sgau
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * SJL
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| MP:0008365 | adenohypophysis hypoplasia | "underdevelopment or reduced size, usually due to a reduced cell number, of the anterior lobe of the pituitary gland" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cdk4tm1Kiyo/Cdk4tm1Kiyo,Lin9tm1Orc/Lin9tm1Orc
Genetic Background: involves: 129S1/Sv
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| MP:0009593 | absent chorion | "absence of the outermost extraembryonic membrane" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctcfltm1.1Vloc/Ctcfltm1.1Vloc
Genetic Background: involves: 129S1/Sv * C57BL/6 * SJL
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| MP:0009762 | abnormal mitotic spindle assembly checkpoint | "an anomaly in the process that normally prevents inaccurate segregation of chromosome by inhibiting cell-cycle progression in response to a signal generated by mitotic spindle damage or by chromosomes that have not attached to microtubules" [PMID:19372138] |
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Allelic Composition: Gt(ROSA)26Sortm1(cre/ERT)Brn/Gt(ROSA)26Sor+,Lin9tm1.1Sgau/Lin9tm1.1Sgau
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * SJL
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| MP:0010157 | abnormal small intestinal crypt cell proliferation | "anomaly in the ability of the cells that make up the tubular intestinal glands found in the mucosal membranes of the small intestine to undergo expansion by cell division" [MGI:jbubier "Jason Bubier, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gt(ROSA)26Sortm1(cre/ERT)Brn/Gt(ROSA)26Sor+,Lin9tm1.1Sgau/Lin9tm1.1Sgau
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * SJL
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| MP:0011095 | complete embryonic lethality between implantation and placentation | "death of all organisms of a given genotype in a population between the point of implantation and the initiation of placentation (Mus: E4.5 to less than E9)" [MGI:csmith] |
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Allelic Composition: Ctcfltm1.1Vloc/Ctcfltm1.1Vloc
Genetic Background: involves: 129S1/Sv * C57BL/6 * SJL
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| MP:0011100 | complete preweaning lethality | "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith] |
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Allelic Composition: Gt(ROSA)26Sortm1(cre/ERT)Brn/Gt(ROSA)26Sor+,Lin9tm1.1Sgau/Lin9tm1.1Sgau
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * SJL
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| MP:0011184 | absent embryonic epiblast | "absence of the tissue derived from the inner cell mass that gives rise to the ectoderm, endoderm and mesoderm of the embryo proper and to the extraembryonic mesoderm" [PMID:21123814] |
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Allelic Composition: Ctcfltm1.1Vloc/Ctcfltm1.1Vloc
Genetic Background: involves: 129S1/Sv * C57BL/6 * SJL
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| MP:0011704 | decreased fibroblast proliferation | "reduction in the expansion rate of a fibroblast cell population by cell division" [MGI:csmith] |
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Allelic Composition: Gt(ROSA)26Sortm1(cre/ERT)Brn/Gt(ROSA)26Sor+,Lin9tm1.1Sgau/Lin9tm1.1Sgau
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * SJL
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| MP:0012114 | absent inner cell mass proliferation | |
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Allelic Composition: Ctcfltm1.1Vloc/Ctcfltm1.1Vloc
Genetic Background: involves: 129S1/Sv * C57BL/6 * SJL
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