ENSMUSG00000059288


Mus musculus

Features
Gene ID: ENSMUSG00000059288
  
Biological name :Cdyl
  
Synonyms : Cdyl / Chromodomain Y-like protein / Q9WTK2
  
Possible biological names infered from orthology : chromodomain Y like / Q9Y232
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: A3.3
Gene start: 35659833
Gene end: 35874063
  
Corresponding Affymetrix probe sets: 10404578 (MoGene1.0st)   1418070_at (Mouse Genome 430 2.0 Array)   1418071_s_at (Mouse Genome 430 2.0 Array)   1448935_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000074707
Ensembl peptide - ENSMUSP00000131784
Ensembl peptide - ENSMUSP00000153274
NCBI entrez gene - 12593     See in Manteia.
MGI - MGI:1339956
RefSeq - XM_006516536
RefSeq - NM_001123386
RefSeq - NM_009881
RefSeq Peptide - NP_001116858
RefSeq Peptide - NP_034011
swissprot - Q9WTK2
swissprot - A0A286YDJ1
Ensembl - ENSMUSG00000059288
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdylENSDARG00000038985Danio rerio
 ENSGALG00000012808Gallus gallus
 CDYLENSG00000153046Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cdyl2 / Q9D5D8 / Chromodomain Y-like protein 2 / Q8N8U2* / chromodomain Y like 2*ENSMUSG0000003175844
Eci2 / Q9WUR2 / Enoyl-CoA delta isomerase 2, mitochondrial / O75521* / enoyl-CoA delta isomerase 2*ENSMUSG0000002141720
Eci3 / Q78JN3 / Enoyl-CoA delta isomerase 3, peroxisomal / ECI2* / O75521* / enoyl-CoA delta isomerase 2*ENSMUSG0000002141617
Echs1 / Q8BH95 / Enoyl-CoA hydratase, mitochondrial / P30084* / enoyl-CoA hydratase, short chain 1*ENSMUSG0000002546512
Auh / AU RNA binding methylglutaconyl-CoA hydratase / Q13825*ENSMUSG0000002146011
Ech1 / O35459 / Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial / Q13011* / enoyl-CoA hydratase 1*ENSMUSG0000005389810
Echdc2 / Q3TLP5 / Enoyl-CoA hydratase domain-containing protein 2, mitochondrial / Q86YB7* / enoyl-CoA hydratase domain containing 2*ENSMUSG0000002860110
Echdc3 / Q9D7J9 / Enoyl-CoA hydratase domain-containing protein 3, mitochondrial / Q96DC8* / enoyl-CoA hydratase domain containing 3*ENSMUSG0000003906310


Protein motifs (from Interpro)
Interpro ID Name
 IPR000953  Chromo/chromo shadow domain
 IPR001753  Enoyl-CoA hydratase/isomerase
 IPR014748  Enoyl-CoA hydratase, C-terminal
 IPR016197  Chromo-like domain superfamily
 IPR017984  Chromo domain subgroup
 IPR023779  Chromo domain, conserved site
 IPR023780  Chromo domain
 IPR029045  ClpP/crotonase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0007286 spermatid development IMP
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016573 histone acetylation IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0060816 random inactivation of X chromosome IDA
 biological_processGO:0120094 negative regulation of peptidyl-lysine crotonylation IDA
 biological_processGO:1903507 negative regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0016607 nuclear speck ISO
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0003714 transcription corepressor activity ISO
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004402 histone acetyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0030674 protein binding, bridging ISO
 molecular_functionGO:0035064 methylated histone binding ISS
 molecular_functionGO:0120092 crotonyl-CoA hydratase activity ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002906 susceptibility to pharmacologically induced seizures "inability to withstand doses of pharmacological drugs that induce seizure activity in normal animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:69504]
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Allelic Composition: Cdyltm1.1Yuw/Cdyltm1.1Yuw,Emx1tm1(cre)Yql/Emx1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0006009 abnormal neuronal migration "defective or impaired movement of immature neurons from germinal zones to specific positions where they will reside as they mature" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Cdyltm1.1Yuw/Cdyltm1.1Yuw,Emx1tm1(cre)Yql/Emx1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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