ENSMUSG00000021416


Mus musculus

Features
Gene ID: ENSMUSG00000021416
  
Biological name :Eci3
  
Synonyms : Eci3 / Enoyl-CoA delta isomerase 3, peroxisomal / Q78JN3
  
Possible biological names infered from orthology : ECI2 / enoyl-CoA delta isomerase 2 / O75521
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: A3.3
Gene start: 34946614
Gene end: 34963810
  
Corresponding Affymetrix probe sets: 10408647 (MoGene1.0st)   1451588_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000021853
Ensembl peptide - ENSMUSP00000132701
NCBI entrez gene - 69123     See in Manteia.
MGI - MGI:1916373
RefSeq - XM_011244343
RefSeq - NM_026947
RefSeq - XM_006516765
RefSeq Peptide - NP_081223
swissprot - Q78JN3
swissprot - E9PY42
Ensembl - ENSMUSG00000021416
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eci2ENSDARG00000102412Danio rerio
 ECI2ENSGALG00000012809Gallus gallus
 ECI2ENSG00000198721Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Eci2 / Q9WUR2 / Enoyl-CoA delta isomerase 2, mitochondrial / O75521* / enoyl-CoA delta isomerase 2*ENSMUSG0000002141779
Cdyl2 / Q9D5D8 / Chromodomain Y-like protein 2 / Q8N8U2* / chromodomain Y like 2*ENSMUSG0000003175832
Cdyl / Q9WTK2 / Chromodomain Y-like protein / Q9Y232* / chromodomain Y like*ENSMUSG0000005928832
Echdc3 / Q9D7J9 / Enoyl-CoA hydratase domain-containing protein 3, mitochondrial / Q96DC8* / enoyl-CoA hydratase domain containing 3*ENSMUSG0000003906321
Echs1 / Q8BH95 / Enoyl-CoA hydratase, mitochondrial / P30084* / enoyl-CoA hydratase, short chain 1*ENSMUSG0000002546521
Auh / AU RNA binding methylglutaconyl-CoA hydratase / Q13825*ENSMUSG0000002146019
Echdc2 / Q3TLP5 / Enoyl-CoA hydratase domain-containing protein 2, mitochondrial / Q86YB7* / enoyl-CoA hydratase domain containing 2*ENSMUSG0000002860119
Ech1 / O35459 / Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial / Q13011* / enoyl-CoA hydratase 1*ENSMUSG0000005389816


Protein motifs (from Interpro)
Interpro ID Name
 IPR000582  Acyl-CoA-binding protein, ACBP
 IPR001753  Enoyl-CoA hydratase/isomerase
 IPR014352  FERM/acyl-CoA-binding protein superfamily
 IPR014748  Enoyl-CoA hydratase, C-terminal
 IPR029045  ClpP/crotonase-like domain superfamily
 IPR035984  Acyl-CoA binding protein superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006635 fatty acid beta-oxidation IC
 biological_processGO:0008152 metabolic process IEA
 cellular_componentGO:0005777 peroxisome IDA
 molecular_functionGO:0000062 fatty-acyl-CoA binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004165 dodecenoyl-CoA delta-isomerase activity IDA
 molecular_functionGO:0016853 isomerase activity IEA


Pathways (from Reactome)
Pathway description
Beta-oxidation of very long chain fatty acids
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005014 increased B cell number "greater than normal B cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Xbp1tm1a(EUCOMM)Wtsi/Xbp1+
Genetic Background: C57BL/6N-Xbp1tm1a(EUCOMM)Wtsi/Ics

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000021416 Eci3 / Q78JN3 / Enoyl-CoA delta isomerase 3, peroxisomal / ECI2* / O75521* / enoyl-CoA delta isomerase 2*  / complex
 ENSMUSG00000021417 Eci2 / Q9WUR2 / Enoyl-CoA delta isomerase 2, mitochondrial / O75521* / enoyl-CoA delta isomerase 2*  / complex






 

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