ENSMUSG00000059493


Mus musculus

Features
Gene ID: ENSMUSG00000059493
  
Biological name :Nhs
  
Synonyms : Nhs / NHS actin remodeling regulator
  
Possible biological names infered from orthology : Q6T4R5
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: F4
Gene start: 161833296
Gene end: 162159730
  
Corresponding Affymetrix probe sets: 10607646 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000084319
Ensembl peptide - ENSMUSP00000080280
NCBI entrez gene - 195727     See in Manteia.
MGI - MGI:2684894
RefSeq - XM_011247800
RefSeq - NM_001081052
RefSeq - NM_001290526
RefSeq - XM_006528765
RefSeq - XM_006528766
RefSeq Peptide - NP_001277455
RefSeq Peptide - NP_001074521
swissprot - B9EJX2
swissprot - B1AV60
Ensembl - ENSMUSG00000059493
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nhsaENSDARG00000070227Danio rerio
 nhsbENSDARG00000079977Danio rerio
 NHSENSGALG00000016543Gallus gallus
 NHSENSG00000188158Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nhsl1 / Q8CAF4 / NHS-like protein 1 / Q5SYE7* / NHS like 1*ENSMUSG0000003983523
Nhsl2 / NHS like 2 / Q5HYW2*ENSMUSG0000007948121


Protein motifs (from Interpro)
Interpro ID Name
 IPR024845  Nance-Horan syndrome protein family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002088 lens development in camera-type eye IMP
 biological_processGO:0030154 cell differentiation IMP
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0016604 nuclear body ISO
 cellular_componentGO:0030054 cell junction ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001303 abnormal lens morphology "malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]
Show

Allelic Composition: Nphs1tm1Rkl/Nphs1tm1Rkl
Genetic Background: involves: 129S2/SvPasCrl

Allelic Composition: NhsXcat/NhsXcat
Genetic Background: involves: DBA/2 * T STOCK

 MP:0001304 cataracts "complete or partial opacity of the lens" [J:65031]
Show

Allelic Composition: Nphs1tm1Rkl/Nphs1tm1Rkl
Genetic Background: involves: 129S2/SvPasCrl

Allelic Composition: NhsXcat/NhsXcat
Genetic Background: involves: DBA/2 * T STOCK

Allelic Composition: NhsXcat/Nhs+
Genetic Background: involves: DBA/2 * T STOCK

 MP:0002840 abnormal lens fibers morphology "structural anomaly of the elongated cells of the crystalline lens of the eye" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Nphs1tm1Rkl/Nphs1tm1Rkl
Genetic Background: involves: 129S2/SvPasCrl

Allelic Composition: NhsXcat/NhsXcat
Genetic Background: involves: DBA/2 * T STOCK

 MP:0003236 abnormal lens capsule morphology "malformation in the elastic, clear, membrane-like structure, that is outer most layer of the lens" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93301]
Show

Allelic Composition: Nphs1tm1Rkl/Nphs1tm1Rkl
Genetic Background: involves: 129S2/SvPasCrl

Allelic Composition: NhsXcat/NhsXcat
Genetic Background: involves: DBA/2 * T STOCK

 MP:0008841 ruptured lens capsule "a break or tear in the elastic, clear, membrane-like structure, that is outer most layer of the lens" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nphs1tm1Rkl/Nphs1tm1Rkl
Genetic Background: involves: 129S2/SvPasCrl

Allelic Composition: NhsXcat/NhsXcat
Genetic Background: involves: DBA/2 * T STOCK

 MP:0010263 total cataracts "a lens opacity which involves both nuclear and cortical regions, including all fibers of a lens; usually congenital" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", ISBN:978-0-8493-0864-2 "Smith R.S. et al (ed.) Systematic Evaluation of the Mouse Eye: Anatomy, Pathology, and Biomethods"]
Show

Allelic Composition: Nphs1tm1Rkl/Nphs1tm1Rkl
Genetic Background: involves: 129S2/SvPasCrl

Allelic Composition: NhsXcat/NhsXcat
Genetic Background: involves: DBA/2 * T STOCK

 MP:0011697 vacuolated lens "fluid filled cavities are present in the cytoplasm of the transparent structure of the eye responsible for focusing light" [MGI:llw2]
Show

Allelic Composition: Nphs1tm1Rkl/Nphs1tm1Rkl
Genetic Background: involves: 129S2/SvPasCrl

Allelic Composition: NhsXcat/NhsXcat
Genetic Background: involves: DBA/2 * T STOCK

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr