ENSMUSG00000059625


Mus musculus

Features
Gene ID: ENSMUSG00000059625
  
Biological name :Sohlh1
  
Synonyms : Q6IUP1 / Sohlh1 / Spermatosis- and oosis-specific basic helix-loop-helix-containing protein 1
  
Possible biological names infered from orthology : Q5JUK2 / spermatogenesis and oogenesis specific basic helix-loop-helix 1
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: A3
Gene start: 25842995
Gene end: 25847248
  
Corresponding Affymetrix probe sets: 10480869 (MoGene1.0st)   1460015_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000076253
NCBI entrez gene - 227631     See in Manteia.
MGI - MGI:2684956
RefSeq - XM_006497875
RefSeq - NM_001001714
RefSeq - XM_006497874
RefSeq Peptide - NP_001001714
swissprot - Q6IUP1
Ensembl - ENSMUSG00000059625
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q5JUK2ENSG00000165643Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR032668  Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001541 ovarian follicle development IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007283 spermatogenesis IDA
 biological_processGO:0009994 oocyte differentiation IDA
 biological_processGO:0010468 regulation of gene expression IMP
 biological_processGO:0030154 cell differentiation IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0048477 oogenesis IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0001046 core promoter sequence-specific DNA binding IBA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046982 protein heterodimerization activity IDA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001932 abnormal spermiogenesis "failure of sperm cells to form or differentiate" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Faahtm1Crv/Faahtm1Crv
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0002216 abnormal seminiferous tubule morphology "malformation of the tubules in the testes where spermatogenesis occurs" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Faahtm1Crv/Faahtm1Crv
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Faahtm1Crv/Faahtm1Crv
Genetic Background: involves: 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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