ENSMUSG00000059654


Mus musculus

Features
Gene ID: ENSMUSG00000059654
  
Biological name :Reg1
  
Synonyms : P43137 / Reg1 / regenerating islet-derived 1
  
Possible biological names infered from orthology : P05451 / P48304 / REG1A / REG1B / regenerating family member 1 alpha / regenerating family member 1 beta
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: C3
Gene start: 78422711
Gene end: 78428667
  
Corresponding Affymetrix probe sets: 10539200 (MoGene1.0st)   1415905_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000078847
Ensembl peptide - ENSMUSP00000144840
Ensembl peptide - ENSMUSP00000145161
NCBI entrez gene - 19692     See in Manteia.
MGI - MGI:97895
RefSeq - NM_009042
RefSeq Peptide - NP_033068
swissprot - P43137
swissprot - Q3TV26
Ensembl - ENSMUSG00000059654
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 REG1AENSG00000115386Homo sapiens
 REG1BENSG00000172023Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Reg2 / Q08731 / regenerating islet-derived 2 / REG1A* / REG1B* / P48304* / P05451* / regenerating family member 1 beta* / regenerating family member 1 alpha*ENSMUSG0000002314079
Reg3g / O09049 / regenerating islet-derived 3 gamma / REG3A* / Q6UW15* / Q06141* / regenerating family member 3 alpha* / regenerating family member 3 gamma*ENSMUSG0000003001746
Reg3b / P35230 / Rerating islet-derived protein 3-beta Rerating islet-derived protein 3-beta 16.5 kDa form Rerating islet-derived protein 3-beta 15 kDa form / REG3G* / REG3A* / Q06141* / Q6...ENSMUSG0000007135643
Reg3d / regenerating islet-derived 3 delta / REG3A* / REG3G* / Q6UW15* / Q06141* / regenerating family member 3 alpha* / regenerating family member 3 gamma*ENSMUSG0000006834143
Reg3a / O09037 / regenerating islet-derived 3 alpha / REG3G* / Q06141* / Q6UW15* / regenerating family member 3 alpha* / regenerating family member 3 gamma*ENSMUSG0000007951642
Reg4 / Q9D8G5 / Rerating islet-derived protein 4 / Q9BYZ8* / regenerating family member 4*ENSMUSG0000002787629


Protein motifs (from Interpro)
Interpro ID Name
 IPR001304  C-type lectin-like
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR018378  C-type lectin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0007494 midgut development IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0014070 response to organic cyclic compound IEA
 biological_processGO:0031667 response to nutrient levels IEA
 biological_processGO:0042060 wound healing IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0051289 protein homotetramerization IEA
 biological_processGO:0055074 calcium ion homeostasis IEA
 biological_processGO:0097421 liver regeneration IEA
 biological_processGO:1903492 response to acetylsalicylate IEA
 biological_processGO:1903861 positive regulation of dendrite extension IEA
 biological_processGO:1904692 positive regulation of type B pancreatic cell proliferation IEA
 biological_processGO:1904699 positive regulation of acinar cell proliferation IEA
 biological_processGO:1990785 response to water-immersion restraint stress IEA
 biological_processGO:1990798 pancreas regeneration IEA
 biological_processGO:1990864 response to growth hormone-releasing hormone IEA
 biological_processGO:1990867 response to gastrin IEA
 biological_processGO:1990869 cellular response to chemokine IEA
 biological_processGO:1990878 cellular response to gastrin IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0030426 growth cone IEA
 cellular_componentGO:0032590 dendrite membrane IEA
 cellular_componentGO:0032809 neuronal cell body membrane IEA
 cellular_componentGO:0042588 zymogen granule IEA
 cellular_componentGO:0045178 basal part of cell IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0008083 growth factor activity ISO
 molecular_functionGO:0019902 phosphatase binding IEA
 molecular_functionGO:0019903 protein phosphatase binding IEA
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002693 abnormal pancreas physiology "abberrant function of the organ that secretes pancreatic juice into the duodenum and secretes glucagon and insulin into the bloodstream" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Nkx3-1tm1Saa/Nkx3-1tm1Saa,Tg(KLK3-cre)13Saa/?
Genetic Background: involves: C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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