ENSMUSG00000059734


Mus musculus

Features
Gene ID: ENSMUSG00000059734
  
Biological name :Ndufs8
  
Synonyms : NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial / Ndufs8 / Q8K3J1
  
Possible biological names infered from orthology : NADH:ubiquinone oxidoreductase core subunit S8 / O00217
  
Species: Mus musculus
  
Chr. number: 19
Strand: -1
Band: A
Gene start: 3908870
Gene end: 3912717
  
Corresponding Affymetrix probe sets: 10464551 (MoGene1.0st)   1423907_a_at (Mouse Genome 430 2.0 Array)   1423908_at (Mouse Genome 430 2.0 Array)   1434212_at (Mouse Genome 430 2.0 Array)   1434213_x_at (Mouse Genome 430 2.0 Array)   1434579_x_at (Mouse Genome 430 2.0 Array)   1455283_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000074600
NCBI entrez gene - 225887     See in Manteia.
MGI - MGI:2385079
RefSeq - NM_144870
RefSeq - NM_001271443
RefSeq - NM_001271444
RefSeq Peptide - NP_001258372
RefSeq Peptide - NP_001258373
RefSeq Peptide - NP_659119
swissprot - Q5M9P5
swissprot - Q8K3J1
Ensembl - ENSMUSG00000059734
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ndufs8aENSDARG00000051986Danio rerio
 ndufs8bENSDARG00000057055Danio rerio
 ENSGALG00000040173Gallus gallus
 NDUFS8ENSG00000110717Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009051  Alpha-helical ferredoxin
 IPR010226  NADH-quinone oxidoreductase, chain I
 IPR017896  4Fe-4S ferredoxin-type, iron-sulphur binding domain
 IPR017900  4Fe-4S ferredoxin, iron-sulphur binding, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0032981 mitochondrial respiratory chain complex I assembly IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005747 mitochondrial respiratory chain complex I IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0070469 respiratory chain IEA
 molecular_functionGO:0003954 NADH dehydrogenase activity ISO
 molecular_functionGO:0008137 NADH dehydrogenase (ubiquinone) activity ISO
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016651 oxidoreductase activity, acting on NAD(P)H IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA
 molecular_functionGO:0051539 4 iron, 4 sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
Respiratory electron transport
Complex I biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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