ENSMUSG00000059824


Mus musculus

Features
Gene ID: ENSMUSG00000059824
  
Biological name :Dbp
  
Synonyms : Dbp / D site-binding protein / Q60925
  
Possible biological names infered from orthology : D-box binding PAR bZIP transcription factor / Q10586
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: B3
Gene start: 45705088
Gene end: 45710203
  
Corresponding Affymetrix probe sets: 10553092 (MoGene1.0st)   1418174_at (Mouse Genome 430 2.0 Array)   1438211_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000079693
Ensembl peptide - ENSMUSP00000147790
Ensembl peptide - ENSMUSP00000147355
NCBI entrez gene - 13170     See in Manteia.
MGI - MGI:94866
RefSeq - NM_016974
RefSeq - XM_006540596
RefSeq Peptide - NP_058670
swissprot - A0A1B0GS46
swissprot - Q60925
swissprot - A0A1B0GR32
Ensembl - ENSMUSG00000059824
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dbpaENSDARG00000063014Danio rerio
 dbpbENSDARG00000057652Danio rerio
 DBPENSG00000105516Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Hlf / Q8BW74 / Hepatic leukemia factor / Q16534* / HLF, PAR bZIP transcription factor*ENSMUSG0000000394940
Tef / Q9JLC6 / Thyrotroph embryonic factor / Q10587* / TEF, PAR bZIP transcription factor*ENSMUSG0000002238938


Protein motifs (from Interpro)
Interpro ID Name
 IPR004827  Basic-leucine zipper domain
 IPR029830  D site-binding protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001889 liver development IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0007623 circadian rhythm IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048511 rhythmic process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
Show

Allelic Composition: Vcam1tm2Flv/Vcam1tm2Flv,Tg(Mx1-cre)1Cgn/0
Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA

 MP:0001496 audiogenic seizures "a reflex seizure triggered by loud noises" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gfra3tm1Wss/Gfra3tm1Wss
Genetic Background: involves: 129X1/SvJ * Black Swiss

 MP:0001905 abnormal dopamine level "greater or less than the normal concentration of this catecholamine neurotransmitter, dervied from tyrosine and the precursor to norepinephrine and epinephrine" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Gfra3tm1Wss/Gfra3tm1Wss
Genetic Background: involves: 129X1/SvJ * Black Swiss

 MP:0002064 seizures "sudden and often acute manifestation of epileptic attack, sometimes convulsive" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gfra3tm1Wss/Gfra3tm1Wss
Genetic Background: involves: 129X1/SvJ * Black Swiss

Allelic Composition: Dbptm1Schb/Dbptm1Schb,Hlftm1Schb/Hlftm1Schb,Teftm1Schb/Tef+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gfra3tm1Wss/Gfra3tm1Wss
Genetic Background: involves: 129X1/SvJ * Black Swiss

Allelic Composition: Dbptm1Schb/Dbptm1Schb,Teftm1Schb/Teftm1Schb
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0002152 abnormal brain morphology "anomalous structure of or abnormal development of the brain, one of the two components of the central nervous system and the center of thought and emotion; controls coordination, bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, http://cancerweb.ncl.ac.uk]
Show

Allelic Composition: Gfra3tm1Wss/Gfra3tm1Wss
Genetic Background: involves: 129X1/SvJ * Black Swiss

 MP:0003216 absence seizures "impairment of consciousness without convulsions associated with widespread bilaterally synchronous spike-and-wave discharges (SWDs) in the electroencephalogram (EEG)" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Gfra3tm1Wss/Gfra3tm1Wss
Genetic Background: involves: 129X1/SvJ * Black Swiss

Allelic Composition: Dbptm1Schb/Dbptm1Schb,Hlftm1Schb/Hlftm1Schb,Teftm1Schb/Tef+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0003997 tonic-clonic seizures "increased number or decreased threshold for the induction of a seizure characterized by initial rigidity followed by rhythmic jerking movements" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Gfra3tm1Wss/Gfra3tm1Wss
Genetic Background: involves: 129X1/SvJ * Black Swiss

 MP:0004994 abnormal brain wave pattern "any anomaly in the standard pattern of rhythmic and rapid fluctuation of electrical potential between parts of the brain, often visualized on an electroencephalogram (EEG); the pattern is often measured to diagnose neurological conditions such as seizure disorders (epilepsy)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Gfra3tm1Wss/Gfra3tm1Wss
Genetic Background: involves: 129X1/SvJ * Black Swiss

Allelic Composition: Dbptm1Schb/Dbptm1Schb,Hlftm1Schb/Hlftm1Schb,Teftm1Schb/Tef+
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0005322 abnormal serotonin level "anomalous concentration of biochemical messenger and regulator, found in the CNS, g.i. tract, and produced by platelets; it mediates neurotransmission, g.i. motility, hemostasis, and cardiovascular integrity " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Gfra3tm1Wss/Gfra3tm1Wss
Genetic Background: involves: 129X1/SvJ * Black Swiss

 MP:0020470 shortened circadian behavior period "decrease in the cycle length of a behavior expressed when exposed to constant conditions without temporal cues" [MGI:smb]
Show

Allelic Composition: Vcam1tm2Flv/Vcam1tm2Flv,Tg(Mx1-cre)1Cgn/0
Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA

 MP:0020477 abnormal locomotor circadian rhythm "any anomaly in the rhythm of the locomotor activity of an organism during its 24 hour activity cycle" [GO:0045475]
Show

Allelic Composition: Vcam1tm2Flv/Vcam1tm2Flv,Tg(Mx1-cre)1Cgn/0
Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr