ENSMUSG00000060166


Mus musculus

Features
Gene ID: ENSMUSG00000060166
  
Biological name :Zdhhc8
  
Synonyms : Q5Y5T5 / Zdhhc8 / zinc finger, DHHC domain containing 8
  
Possible biological names infered from orthology : Q9ULC8 / zinc finger DHHC-type containing 8
  
Species: Mus musculus
  
Chr. number: 16
Strand: -1
Band: A3
Gene start: 18220754
Gene end: 18235136
  
Corresponding Affymetrix probe sets: 10438293 (MoGene1.0st)   1436468_at (Mouse Genome 430 2.0 Array)   1451476_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000076224
NCBI entrez gene - 27801     See in Manteia.
MGI - MGI:1338012
RefSeq - XM_006522224
RefSeq - NM_172151
RefSeq - XM_006522223
RefSeq Peptide - NP_742163
swissprot - Q5Y5T5
Ensembl - ENSMUSG00000060166
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zdhhc8bENSDARG00000018508Danio rerio
 ZDHHC8ENSGALG00000002124Gallus gallus
 Q9ULC8ENSG00000099904Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8VDZ4 / Zdhhc5 / zinc finger, DHHC domain containing 5 / Q9C0B5* / zinc finger DHHC-type containing 5*ENSMUSG0000003407549
Q8BQQ1 / Zdhhc14 / zinc finger, DHHC domain containing 14 / Q8IZN3* / zinc finger DHHC-type containing 14*ENSMUSG0000003426520
P59268 / Zdhhc9 / zinc finger, DHHC domain containing 9 / Q9Y397* / zinc finger DHHC-type containing 9*ENSMUSG0000003698517
Q5Y5T2 / Zdhhc18 / zinc finger, DHHC domain containing 18 / Q9NUE0* / zinc finger DHHC-type containing 18*ENSMUSG0000003755315
Q810M5 / Zdhhc19 / zinc finger, DHHC domain containing 19 / Q8WVZ1* / zinc finger DHHC-type containing 19*ENSMUSG0000005236314
Q8R0N9 / Zdhhc1 / zinc finger, DHHC domain containing 1 / Q8WTX9* / zinc finger DHHC-type containing 1*ENSMUSG0000003919914
Q14AK4 / Zdhhc11 / zinc finger, DHHC domain containing 11 / Q9H8X9* / P0C7U3* / ZDHHC11B* / zinc finger DHHC-type containing 11* / zinc finger DHHC-type containing 11B*ENSMUSG000000691899


Protein motifs (from Interpro)
Interpro ID Name
 IPR001594  Palmitoyltransferase, DHHC domain
 IPR030291  Palmitoyltransferase ZDHHC8


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007626 locomotory behavior IMP
 biological_processGO:0018345 protein palmitoylation IBA
 biological_processGO:1903146 regulation of autophagy of mitochondrion IEA
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016409 palmitoyltransferase activity IBA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0019706 protein-cysteine S-palmitoyltransferase activity IEA


Pathways (from Reactome)
Pathway description
HDL assembly


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001417 decreased exploration in new environment "less amount of time spent investigating a new location" [J:79870]
Show

Allelic Composition: Mybtm1Cgn/Mybtm1Cgn,Tg(Lck-cre)1Cwi/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2

Allelic Composition: Zdhhc8tm1Kara/Zdhhc8+
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0008143 abnormal dendrite morphology "any structural anomaly of the highly branched tree-like process of a neuron that serves as a receptive field and conducts impulses toward the cell body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mex3btm1.1Mbld/Mex3btm1.1Mbld,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: C57BL/6 * SJL

Allelic Composition: Zdhhc8tm1Kara/Zdhhc8+
Genetic Background: Not Specified

 MP:0009142 decreased prepulse inhibition "decrease in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mybtm1Cgn/Mybtm1Cgn,Tg(Lck-cre)1Cwi/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2

 MP:0009538 abnormal synapse morphology "any strucutral anomaly of the membrane junction site of a nerve cell to a target cell, such as another nerve cell, an effector cell, or a sensory receptor cell; transmission of nerve impulses may be mediated by chemical or by electrical means" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MESH:A08.850]
Show

Allelic Composition: Mex3btm1.1Mbld/Mex3btm1.1Mbld,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: C57BL/6 * SJL

Allelic Composition: Zdhhc8tm1Kara/Zdhhc8+
Genetic Background: Not Specified

 MP:0009936 abnormal dendritic spine morphology "any structural anomaly of the small membranous protrusion from the dendrite of a neuron that is involved in synaptic transmission; it typically receives input from a single synapse of an axon" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mex3btm1.1Mbld/Mex3btm1.1Mbld,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: C57BL/6 * SJL

Allelic Composition: Zdhhc8tm1Kara/Zdhhc8+
Genetic Background: Not Specified

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000015243 Abca1 / P41233 / ATP-binding cassette, sub-family A (ABC1), member 1 / O95477* / ATP binding cassette subfamily A member 1*  / reaction






 

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