ENSMUSG00000062184


Mus musculus

Features
Gene ID: ENSMUSG00000062184
  
Biological name :Hs6st2
  
Synonyms : Heparan-sulfate 6-O-sulfotransferase 2 / Hs6st2 / Q80UW0
  
Possible biological names infered from orthology : Q96MM7
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: A5
Gene start: 51387212
Gene end: 51681856
  
Corresponding Affymetrix probe sets: 10604542 (MoGene1.0st)   1420938_at (Mouse Genome 430 2.0 Array)   1420939_at (Mouse Genome 430 2.0 Array)   1446257_at (Mouse Genome 430 2.0 Array)   1450047_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000110521
Ensembl peptide - ENSMUSP00000085497
NCBI entrez gene - 50786     See in Manteia.
MGI - MGI:1354959
RefSeq - NM_015819
RefSeq - XM_006541519
RefSeq - NM_001077202
RefSeq - NM_001290467
RefSeq - NM_001290468
RefSeq - XM_006541516
RefSeq - XM_006541518
RefSeq Peptide - NP_056634
RefSeq Peptide - NP_001070670
RefSeq Peptide - NP_001277396
RefSeq Peptide - NP_001277397
swissprot - Q80UW0
Ensembl - ENSMUSG00000062184
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hs6st3bENSDARG00000069500Danio rerio
 HS6ST2ENSGALG00000034250Gallus gallus
 HS6ST2ENSG00000171004Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Hs6st3 / Q9QYK4 / Heparan-sulfate 6-O-sulfotransferase 3 / Q8IZP7*ENSMUSG0000005346538
Hs6st1 / Q9QYK5 / Heparan-sulfate 6-O-sulfotransferase 1 / O60243*ENSMUSG0000004521626


Protein motifs (from Interpro)
Interpro ID Name
 IPR005331  Sulfotransferase
 IPR010635  Heparan sulphate 6-sulfotransferase/Protein-tyrosine sulfotransferase
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification IDA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0008146 sulfotransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0017095 heparan sulfate 6-O-sulfotransferase activity IDA


Pathways (from Reactome)
Pathway description
HS-GAG biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000352 decreased cell proliferation "less than the normal growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Myo5argsc11/Myo5argsc11
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Itktm1Lex/Itktm1Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

Allelic Composition: Hs6st2tm1Lex/Y
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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