ENSMUSG00000063275


Mus musculus

Features
Gene ID: ENSMUSG00000063275
  
Biological name :Hacd1
  
Synonyms : 3-hydroxyacyl-CoA dehydratase 1 / Hacd1
  
Possible biological names infered from orthology : B0YJ81
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: A1
Gene start: 13850282
Gene end: 14056135
  
Corresponding Affymetrix probe sets: 10480249 (MoGene1.0st)   10489343 (MoGene1.0st)   1456315_a_at (Mouse Genome 430 2.0 Array)   1457434_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000088998
Ensembl peptide - ENSMUSP00000141406
Ensembl peptide - ENSMUSP00000110401
Ensembl peptide - ENSMUSP00000074397
NCBI entrez gene - 30963     See in Manteia.
MGI - MGI:1353592
RefSeq - XM_011238977
RefSeq - NM_001012396
RefSeq - NM_013935
RefSeq Peptide - NP_001012396
RefSeq Peptide - NP_038963
swissprot - B9EHK9
swissprot - A2AQ81
Ensembl - ENSMUSG00000063275
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hacd1ENSDARG00000103744Danio rerio
 HACD1ENSGALG00000008659Gallus gallus
 HACD1ENSG00000165996Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Hacd2 / Q9D3B1 / Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 / Q6Y1H2* / 3-hydroxyacyl-CoA dehydratase 2*ENSMUSG0000003537657
Hacd3 / Q8K2C9 / Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 / Q9P035* / 3-hydroxyacyl-CoA dehydratase 3*ENSMUSG0000003362924
Hacd4 / A2AKM2 / Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4 / Q5VWC8* / 3-hydroxyacyl-CoA dehydratase 4*ENSMUSG0000002849719


Protein motifs (from Interpro)
Interpro ID Name
 IPR007482  Protein-tyrosine phosphatase-like, PTPLA


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006633 fatty acid biosynthetic process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0102158 very-long-chain 3-hydroxyacyl-CoA dehydratase activity IEA
 molecular_functionGO:0102343 3-hydroxy-arachidoyl-CoA dehydratase activity IEA
 molecular_functionGO:0102344 3-hydroxy-behenoyl-CoA dehydratase activity IEA
 molecular_functionGO:0102345 3-hydroxy-lignoceroyl-CoA dehydratase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of very long-chain fatty acyl-CoAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Pgrmc1tm1.1Jjp/Pgrmc1tm1.1Jjp,Pgrmc2tm1.1Jjp/Pgrmc2+,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Pgrmc1tm1.1Jjp/Pgrmc1tm1.1Jjp,Pgrmc2tm1.1Jjp/Pgrmc2+,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0005584 abnormal enzyme/coenzyme activity "altered ability of any of these proteins, or their cofactors, to act as catalysts to induce chemical changes in other substances" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Pgrmc1tm1.1Jjp/Pgrmc1tm1.1Jjp,Pgrmc2tm1.1Jjp/Pgrmc2+,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Hacd1tm1Akih/Hacd1+
Genetic Background: B6.129P2-Hacd1tm1Akih

 MP:0009422 decreased gastrocnemius weight "reduction in the weight of the two-headed large muscle of the posterior portion of the lower hindleg, the most superficial of the calf muscles" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Pgrmc1tm1.1Jjp/Pgrmc1tm1.1Jjp,Pgrmc2tm1.1Jjp/Pgrmc2+,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr