ENSMUSG00000064061


Mus musculus

Features
Gene ID: ENSMUSG00000064061
  
Biological name :Dzip3
  
Synonyms : Dzip3 / E3 ubiquitin-protein ligase DZIP3 / Q7TPV2
  
Possible biological names infered from orthology : DAZ interacting zinc finger protein 3 / Q86Y13
  
Species: Mus musculus
  
Chr. number: 16
Strand: -1
Band: B5
Gene start: 48924232
Gene end: 48994165
  
Corresponding Affymetrix probe sets: 10439798 (MoGene1.0st)   1432868_at (Mouse Genome 430 2.0 Array)   1444058_at (Mouse Genome 430 2.0 Array)   1448015_at (Mouse Genome 430 2.0 Array)   1454393_at (Mouse Genome 430 2.0 Array)   1454878_at (Mouse Genome 430 2.0 Array)   1458439_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000110161
Ensembl peptide - ENSMUSP00000113344
Ensembl peptide - ENSMUSP00000117675
NCBI entrez gene - 224170     See in Manteia.
MGI - MGI:1917433
RefSeq - XM_017316969
RefSeq - NM_027341
RefSeq - XM_006522089
RefSeq - XM_006522090
RefSeq - XM_017316967
RefSeq - XM_017316968
RefSeq - NM_001110017
RefSeq Peptide - NP_001103487
RefSeq Peptide - NP_081617
swissprot - F6Z1P8
swissprot - Q7TPV2
swissprot - E9QNZ2
Ensembl - ENSMUSG00000064061
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DZIP3ENSG00000198919Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ttc3 / tetratricopeptide repeat domain 3 / P53804*ENSMUSG0000004078517
Q8BFU3 / Rnf214 / RING finger protein 214 / Q8ND24*ENSMUSG0000004279010


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR033103  E3 ubiquitin-protein ligase DZIP3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway IBA
 biological_processGO:0030968 endoplasmic reticulum unfolded protein response IBA
 cellular_componentGO:0000836 Hrd1p ubiquitin ligase complex IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0036513 Derlin-1 retrotranslocation complex IBA
 cellular_componentGO:0044322 endoplasmic reticulum quality control compartment IBA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity ISO
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019902 phosphatase binding ISS
 molecular_functionGO:0031593 polyubiquitin modification-dependent protein binding ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051082 unfolded protein binding IBA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA
 molecular_functionGO:1990381 ubiquitin-specific protease binding IBA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0008762 embryonic lethality "death of an animal in the embryonic period (Mus: up to E14)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Bach2m2Anu/Bach2m2Anu
Genetic Background: C57BL/6NCrlAnu-Bach2m2Anu

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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