ENSMUSG00000064267


Mus musculus

Features
Gene ID: ENSMUSG00000064267
  
Biological name :Hvcn1
  
Synonyms : Hvcn1 / Mus musculus hydrogen voltage-gated channel 1 (Hvcn1), transcript variant 3, mRNA. / Q3U2S8
  
Possible biological names infered from orthology : hydrogen voltage gated channel 1 / Q96D96
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: F
Gene start: 122206804
Gene end: 122242297
  
Corresponding Affymetrix probe sets: 10525365 (MoGene1.0st)   1424032_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000143483
Ensembl peptide - ENSMUSP00000098312
Ensembl peptide - ENSMUSP00000118013
Ensembl peptide - ENSMUSP00000118151
Ensembl peptide - ENSMUSP00000072401
NCBI entrez gene - 74096     See in Manteia.
MGI - MGI:1921346
RefSeq - XM_011248243
RefSeq - NM_001042489
RefSeq - NM_001359454
RefSeq - NM_028752
RefSeq - XM_006530471
RefSeq - XM_006530472
RefSeq - XM_006530473
RefSeq Peptide - NP_083028
RefSeq Peptide - NP_001346383
RefSeq Peptide - NP_001035954
swissprot - A0A0G2JGA0
swissprot - Q3U2S8
swissprot - D3Z019
swissprot - D3YZ46
Ensembl - ENSMUSG00000064267
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hvcn1ENSDARG00000040338Danio rerio
 HVCN1ENSGALG00000004562Gallus gallus
 HVCN1ENSG00000122986Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8BZB3 / Tmem266 / Transmembrane protein 266 / Q2M3C6*ENSMUSG0000003231320


Protein motifs (from Interpro)
Interpro ID Name
 IPR005821  Ion transport domain
 IPR031844  Voltage-gated hydrogen channel 1, C-terminal membrane-localisation domain
 IPR031846  Voltage-gated hydrogen channel 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0009268 response to pH IDA
 biological_processGO:0010043 response to zinc ion IDA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071294 cellular response to zinc ion IEA
 biological_processGO:0071467 cellular response to pH IEA
 biological_processGO:1902600 proton transmembrane transport IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IC
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0030171 voltage-gated proton channel activity ISO
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Sperm Motility And Taxes
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002451 abnormal macrophage physiology "abnormal function or response of the phagocytic leukocytes involved in innate immunity, early non-adaptive phases of host-defense, antigen presentation, and which act as effector cells in humoral and cell-mediated immunity" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Il6sttm2Thir/Il6sttm2Thir
Genetic Background: B6.Cg-Il6sttm2Thir

 MP:0002463 abnormal neutrophil physiology "abnormal function of these granular leukocytes, which stain with neutral dyes" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Il6sttm2Thir/Il6sttm2Thir
Genetic Background: B6.Cg-Il6sttm2Thir

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000064267 Hvcn1 / Q3U2S8 / Mus musculus hydrogen voltage-gated channel 1 (Hvcn1), transcript variant 3, mRNA. / Q96D96* / hydrogen voltage gated channel 1*  / complex






 

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