ENSMUSG00000064302


Mus musculus

Features
Gene ID: ENSMUSG00000064302
  
Biological name :Clasp1
  
Synonyms : Clasp1 / Mus musculus CLIP associating protein 1 (Clasp1), transcript variant 10, mRNA.
  
Possible biological names infered from orthology : cytoplasmic linker associated protein 1 / Q7Z460
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: E2.3
Gene start: 118389058
Gene end: 118612678
  
Corresponding Affymetrix probe sets: 10349249 (MoGene1.0st)   1427353_at (Mouse Genome 430 2.0 Array)   1452265_at (Mouse Genome 430 2.0 Array)   1459233_at (Mouse Genome 430 2.0 Array)   1460102_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000137137
Ensembl peptide - ENSMUSP00000128089
Ensembl peptide - ENSMUSP00000139526
Ensembl peptide - ENSMUSP00000145100
Ensembl peptide - ENSMUSP00000144818
Ensembl peptide - ENSMUSP00000144798
Ensembl peptide - ENSMUSP00000142203
Ensembl peptide - ENSMUSP00000141582
Ensembl peptide - ENSMUSP00000141105
Ensembl peptide - ENSMUSP00000140860
Ensembl peptide - ENSMUSP00000140778
Ensembl peptide - ENSMUSP00000140665
Ensembl peptide - ENSMUSP00000140593
Ensembl peptide - ENSMUSP00000140167
Ensembl peptide - ENSMUSP00000140095
Ensembl peptide - ENSMUSP00000140019
Ensembl peptide - ENSMUSP00000139619
Ensembl peptide - ENSMUSP00000042266
Ensembl peptide - ENSMUSP00000067858
NCBI entrez gene - 76707     See in Manteia.
MGI - MGI:1923957
RefSeq - XM_017312819
RefSeq - XM_017312747
RefSeq - XM_017312749
RefSeq - XM_017312750
RefSeq - XM_017312751
RefSeq - XM_017312754
RefSeq - XM_017312756
RefSeq - XM_017312757
RefSeq - XM_017312762
RefSeq - XM_017312764
RefSeq - XM_017312767
RefSeq - XM_017312769
RefSeq - XM_017312770
RefSeq - XM_017312771
RefSeq - XM_017312773
RefSeq - XM_017312777
RefSeq - XM_017312783
RefSeq - XM_017312784
RefSeq - XM_017312787
RefSeq - XM_017312793
RefSeq - XM_017312796
RefSeq - XM_017312799
RefSeq - XM_017312807
RefSeq - XM_017312814
RefSeq - XM_017312817
RefSeq - NM_001293300
RefSeq - NM_001293301
RefSeq - NM_001359331
RefSeq - NM_001359334
RefSeq - NM_029709
RefSeq - XM_006529920
RefSeq - XM_006529922
RefSeq - XM_006529924
RefSeq - XM_006529929
RefSeq - XM_006529937
RefSeq - XM_006529938
RefSeq - XM_006529939
RefSeq - XM_006529942
RefSeq - XM_006529943
RefSeq - XM_006529948
RefSeq - XM_006529949
RefSeq - XM_011248107
RefSeq - XM_011248108
RefSeq - XM_017312724
RefSeq - XM_017312725
RefSeq - XM_017312727
RefSeq - XM_017312733
RefSeq - XM_017312734
RefSeq - XM_017312736
RefSeq - XM_017312737
RefSeq - XM_017312738
RefSeq - XM_017312744
RefSeq Peptide - NP_001346274
RefSeq Peptide - NP_001346275
RefSeq Peptide - NP_083985
RefSeq Peptide - NP_001346263
RefSeq Peptide - NP_001280229
RefSeq Peptide - NP_001280230
RefSeq Peptide - NP_001346260
swissprot - A0A087WS18
swissprot - A0A087WRU7
swissprot - A0A087WRK0
swissprot - A0A087WRE8
swissprot - A0A087WQF1
swissprot - E9QNY9
swissprot - A0A087WQ31
swissprot - J3QP81
swissprot - A0A087WP42
swissprot - A0A087WNW8
swissprot - A0A087WQ95
swissprot - E9QKH0
swissprot - E9Q6L0
swissprot - A0A0N4SVH2
swissprot - A0A0N4SUT7
swissprot - A0A0A6YXZ1
swissprot - A0A0A6YWK1
Ensembl - ENSMUSG00000064302
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 clasp1aENSDARG00000010280Danio rerio
 CLASP1ENSGALG00000011645Gallus gallus
 CLASP1ENSG00000074054Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Clasp2 / CLIP-associating protein 2 isoform g / O75122* / cytoplasmic linker associated protein 2*ENSMUSG0000003339259


Protein motifs (from Interpro)
Interpro ID Name
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR021133  HEAT, type 2
 IPR024395  CLASP N-terminal domain
 IPR028399  CLIP-associating protein 1
 IPR034085  TOG domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000226 microtubule cytoskeleton organization IEA
 biological_processGO:0001578 microtubule bundle formation IEA
 biological_processGO:0006903 vesicle targeting IEA
 biological_processGO:0007020 microtubule nucleation IEA
 biological_processGO:0007026 negative regulation of microtubule depolymerization IEA
 biological_processGO:0007030 Golgi organization IEA
 biological_processGO:0007052 mitotic spindle organization IEA
 biological_processGO:0010458 exit from mitosis IEA
 biological_processGO:0010470 regulation of gastrulation IEA
 biological_processGO:0010634 positive regulation of epithelial cell migration IEA
 biological_processGO:0010717 regulation of epithelial to mesenchymal transition IEA
 biological_processGO:0030953 astral microtubule organization IEA
 biological_processGO:0031023 microtubule organizing center organization IEA
 biological_processGO:0031111 negative regulation of microtubule polymerization or depolymerization IEA
 biological_processGO:0034453 microtubule anchoring IEA
 biological_processGO:0040001 establishment of mitotic spindle localization IEA
 biological_processGO:0045921 positive regulation of exocytosis IEA
 biological_processGO:0051294 establishment of spindle orientation IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051497 negative regulation of stress fiber assembly IEA
 biological_processGO:0051893 regulation of focal adhesion assembly IEA
 biological_processGO:0070507 regulation of microtubule cytoskeleton organization IEA
 biological_processGO:0090091 positive regulation of extracellular matrix disassembly IEA
 biological_processGO:1903690 negative regulation of wound healing, spreading of epidermal cells IEA
 biological_processGO:1904261 positive regulation of basement membrane assembly involved in embryonic body morphogenesis IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005828 kinetochore microtubule IEA
 cellular_componentGO:0005876 spindle microtubule IEA
 cellular_componentGO:0005881 cytoplasmic microtubule IEA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0030981 cortical microtubule cytoskeleton IEA
 cellular_componentGO:0031592 centrosomal corona IEA
 cellular_componentGO:0045180 basal cortex IEA
 molecular_functionGO:0002162 dystroglycan binding IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0043515 kinetochore binding IEA
 molecular_functionGO:0051010 microtubule plus-end binding IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
RHO GTPases Activate Formins
Mitotic Prometaphase
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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