ENSMUSG00000066235


Mus musculus

Features
Gene ID: ENSMUSG00000066235
  
Biological name :Pomgnt2
  
Synonyms : Pomgnt2 / Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 / Q8BW41
  
Possible biological names infered from orthology : protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) / Q8NAT1
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: F4
Gene start: 121981606
Gene end: 121997110
  
Corresponding Affymetrix probe sets: 10597878 (MoGene1.0st)   1435677_at (Mouse Genome 430 2.0 Array)   1436489_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000150975
Ensembl peptide - ENSMUSP00000149753
Ensembl peptide - ENSMUSP00000151099
Ensembl peptide - ENSMUSP00000149999
Ensembl peptide - ENSMUSP00000095868
Ensembl peptide - ENSMUSP00000149077
NCBI entrez gene - 215494     See in Manteia.
MGI - MGI:2143424
RefSeq - XM_011242955
RefSeq - NM_001289558
RefSeq - NM_001289559
RefSeq - NM_001289560
RefSeq - NM_153540
RefSeq Peptide - NP_001276487
RefSeq Peptide - NP_001276488
RefSeq Peptide - NP_001276489
RefSeq Peptide - NP_705768
swissprot - A0A1L1SUZ1
swissprot - A0A1L1SV90
swissprot - Q8BW41
swissprot - A0A1L1SSQ2
Ensembl - ENSMUSG00000066235
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q5NDE5ENSDARG00000010941Danio rerio
 Q5NDE8ENSGALG00000011518Gallus gallus
 Q8NAT1ENSG00000144647Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Eogt / Q8BYW9 / EGF domain-specific O-linked N-acetylglucosamine transferase / Q5NDL2*ENSMUSG0000003524517


Protein motifs (from Interpro)
Interpro ID Name
 IPR003961  Fibronectin type III
 IPR007657  Glycosyltransferase 61
 IPR013783  Immunoglobulin-like fold
 IPR036116  Fibronectin type III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001764 neuron migration IMP
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0006493 protein O-linked glycosylation IEA
 biological_processGO:0035269 protein O-linked mannosylation IMP
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008375 acetylglucosaminyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0097363 protein O-GlcNAc transferase activity ISO


Pathways (from Reactome)
Pathway description
O-linked glycosylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000788 abnormal cerebral cortex morphology "malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857]
Show

Allelic Composition: Tg(VDR*L233S,luc)T807Pike/0,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0004200 reduced fetal size "smaller proportions of a fetus compared to littermates (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tg(VDR*L233S,luc)T807Pike/0,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0004273 abnormal basal lamina morphology "anomaly in the structure of the sheet of extracellular matrix characteristically situated under epithelial cells, around muscles, nerves, capillaries, and fat cells, and situated between these elements and the underlying or surrounding connective tissue" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Tg(VDR*L233S,luc)T807Pike/0,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0005584 abnormal enzyme/coenzyme activity "altered ability of any of these proteins, or their cofactors, to act as catalysts to induce chemical changes in other substances" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tg(VDR*L233S,luc)T807Pike/0,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0006009 abnormal neuronal migration "defective or impaired movement of immature neurons from germinal zones to specific positions where they will reside as they mature" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Tg(VDR*L233S,luc)T807Pike/0,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0009674 decreased birth weight "reduction in average weight at birth compared to controls" [RGD:cur "Rat Genome Database submission"]
Show

Allelic Composition: Tg(VDR*L233S,luc)T807Pike/0,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0009703 decreased birth body size "reduction in average body size at birth compared to controls" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tg(VDR*L233S,luc)T807Pike/0,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Tg(VDR*L233S,luc)T807Pike/0,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0020391 radial glial endfoot detachment "detachment of the radial glia cell endfoot from the pial basement membrane" [MGI:anna, PMID:17715063, PMID:23217742, PMID:24256719]
Show

Allelic Composition: Tg(VDR*L233S,luc)T807Pike/0,Vdrtm1Mbd/Vdrtm1Mbd
Genetic Background: involves: 129S4/SvJae * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000039952 Dag1 / Q62165 / Dystroglycan Alpha-dystroglycan Beta-dystroglycan / Q14118* / dystroglycan 1*  / reaction






 

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