ENSMUSG00000068184


Mus musculus

Features
Gene ID: ENSMUSG00000068184
  
Biological name :Ndufaf2
  
Synonyms : NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 / Ndufaf2 / Q59J78
  
Possible biological names infered from orthology : NADH:ubiquinone oxidoreductase complex assembly factor 2 / Q8N183
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: D2.1
Gene start: 108002715
Gene end: 108158623
  
Corresponding Affymetrix probe sets: 10412054 (MoGene1.0st)   1452923_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000130532
Ensembl peptide - ENSMUSP00000153552
Ensembl peptide - ENSMUSP00000153480
Ensembl peptide - ENSMUSP00000153468
NCBI entrez gene - 75597     See in Manteia.
MGI - MGI:1922847
RefSeq - XM_006517779
RefSeq - NM_001127346
RefSeq Peptide - NP_001120818
swissprot - A0A286YE33
swissprot - A0A286YE75
swissprot - Q59J78
swissprot - A0A286YDL9
Ensembl - ENSMUSG00000068184
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ndufaf2ENSDARG00000069286Danio rerio
 NDUFAF2ENSGALG00000027564Gallus gallus
 Q8N183ENSG00000164182Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007763  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:0022904 respiratory electron transport chain IMP
 biological_processGO:0045333 cellular respiration IMP
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus IMP
 biological_processGO:0072593 reactive oxygen species metabolic process IMP
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0008137 NADH dehydrogenase (ubiquinone) activity IEA
 molecular_functionGO:0009055 electron transfer activity IEA


Pathways (from Reactome)
Pathway description
Complex I biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ednratm6(Edn1)Hku/Ednra+
Genetic Background: involves: 129 * C57BL/6 * ICR

 MP:0010956 abnormal mitochondrial ATP synthesis coupled electron transport "anomaly in the transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP, as it occurs in the mitochondrial inner membrane and mediated by multisubunit enzyme complexes known as complex I-IV" [GO:0042775, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cd19tm1.1Oao/Cd19+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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