ENSMUSG00000068874


Mus musculus

Features
Gene ID: ENSMUSG00000068874
  
Biological name :Selenbp1
  
Synonyms : P17563 / Selenbp1 / Selenium-binding protein 1
  
Possible biological names infered from orthology : Q13228
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: F2.1
Gene start: 94933056
Gene end: 94944758
  
Corresponding Affymetrix probe sets: 10494114 (MoGene1.0st)   1417580_s_at (Mouse Genome 430 2.0 Array)   1450699_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000118563
Ensembl peptide - ENSMUSP00000120159
Ensembl peptide - ENSMUSP00000088349
NCBI entrez gene - 20341     See in Manteia.
MGI - MGI:96825
RefSeq - NM_009150
RefSeq Peptide - NP_033176
swissprot - D6RHN2
swissprot - P17563
Ensembl - ENSMUSG00000068874
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 selenbp1ENSDARG00000024717Danio rerio
 ENSGALG00000042695Gallus gallus
 ENSGALG00000018415Gallus gallus
 ENSGALG00000044765Gallus gallus
 SELENBP1ENSGALG00000000866Gallus gallus
 Q13228ENSG00000143416Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Selenbp2 / Q13228* / SELENBP1* / selenium binding protein 1*ENSMUSG0000006887797


Protein motifs (from Interpro)
Interpro ID Name
 IPR008826  Selenium-binding protein
 IPR011042  Six-bladed beta-propeller, TolB-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0050873 brown fat cell differentiation IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0001650 fibrillar center ISO
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0008430 selenium binding IEA
 molecular_functionGO:0018549 methanethiol oxidase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002176 high brain weight "greater than average weight of the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2a+,Tg(CAG-Bgeo,-tTA,-EGFP)2A11Kuw/0,Tg(Pdx1-cre)6Tuv/0,Tg(tetO-MYC)36Bop/0
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6J * FVB/N * SJL

 MP:0002682 reduced number of mature ovarian follicles "fewer than normal numbers of spehroidal cell aggregations in the ovary containing the ovum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Cdkn2atm1Rdp/Cdkn2a+,Tg(CAG-Bgeo,-tTA,-EGFP)2A11Kuw/0,Tg(Pdx1-cre)6Tuv/0,Tg(tetO-MYC)36Bop/0
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6J * FVB/N * SJL

 MP:0002965 hyperalbuminemia "blood albumin concentration above the normal range" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]
Show

Allelic Composition: Cdkn2atm1Rdp/Cdkn2a+,Tg(CAG-Bgeo,-tTA,-EGFP)2A11Kuw/0,Tg(Pdx1-cre)6Tuv/0,Tg(tetO-MYC)36Bop/0
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6J * FVB/N * SJL

 MP:0003402 decreased liver weight "reduced average weight of the bile-secreting exocrine gland" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cdkn2atm1Rdp/Cdkn2a+,Tg(CAG-Bgeo,-tTA,-EGFP)2A11Kuw/0,Tg(Pdx1-cre)6Tuv/0,Tg(tetO-MYC)36Bop/0
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6J * FVB/N * SJL

 MP:0004953 decreased spleen weight "reduction in the average weight of the organ that functions to filter blood and to store red corpuscles and platelets" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cdkn2atm1Rdp/Cdkn2a+,Tg(CAG-Bgeo,-tTA,-EGFP)2A11Kuw/0,Tg(Pdx1-cre)6Tuv/0,Tg(tetO-MYC)36Bop/0
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6J * FVB/N * SJL

 MP:0004955 increased thymus weight "greater than average weight of the primary lymphoid organ that is required for maturation of T cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cdkn2atm1Rdp/Cdkn2a+,Tg(CAG-Bgeo,-tTA,-EGFP)2A11Kuw/0,Tg(Pdx1-cre)6Tuv/0,Tg(tetO-MYC)36Bop/0
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6J * FVB/N * SJL

 MP:0005584 abnormal enzyme/coenzyme activity "altered ability of any of these proteins, or their cofactors, to act as catalysts to induce chemical changes in other substances" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Inpp5aGt(OST50073)Lex/Inpp5a+
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

Allelic Composition: Selenbp1tm1b(KOMP)Wtsi/Selenbp1+
Genetic Background: C57BL/6N-Selenbp1tm1b(KOMP)Wtsi/Mbp

 MP:0009642 abnormal blood homeostasis "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions or chemical or protein composition of the blood" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Inpp5aGt(OST50073)Lex/Inpp5a+
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

Allelic Composition: Selenbp1tm1b(KOMP)Wtsi/Selenbp1+
Genetic Background: C57BL/6N-Selenbp1tm1b(KOMP)Wtsi/Mbp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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