ENSMUSG00000069495


Mus musculus

Features
Gene ID: ENSMUSG00000069495
  
Biological name :Epc2
  
Synonyms : Enhancer of polycomb homolog 2 / Epc2 / Q8C0I4
  
Possible biological names infered from orthology : Q52LR7
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: C1.1
Gene start: 49451486
Gene end: 49551948
  
Corresponding Affymetrix probe sets: 10471978 (MoGene1.0st)   1455317_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000119134
Ensembl peptide - ENSMUSP00000089758
NCBI entrez gene - 227867     See in Manteia.
MGI - MGI:1278321
RefSeq - NM_172663
RefSeq - XM_006498011
RefSeq Peptide - NP_766251
swissprot - A2AQV0
swissprot - Q8C0I4
Ensembl - ENSMUSG00000069495
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 epc2ENSDARG00000007485Danio rerio
 EPC2ENSGALG00000012453Gallus gallus
 EPC2ENSG00000135999Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Epc1 / Q8C9X6 / Enhancer of polycomb homolog 1 / Q9H2F5*ENSMUSG0000002424053


Protein motifs (from Interpro)
Interpro ID Name
 IPR009607  Enhancer of polycomb, C-terminal
 IPR019542  Enhancer of polycomb-like, N-terminal
 IPR024943  Enhancer of polycomb protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0016573 histone acetylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0032777 Piccolo NuA4 histone acetyltransferase complex IEA
 cellular_componentGO:0035267 NuA4 histone acetyltransferase complex IEA
 molecular_functionGO:0004402 histone acetyltransferase activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001303 abnormal lens morphology "malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]
Show

Allelic Composition: Epas1tm1b(EUCOMM)Hmgu/Epas1+
Genetic Background: C57BL/6N-Epas1tm1b(EUCOMM)Hmgu/H

 MP:0004599 abnormal vertebral arch morphology "any structural anomaly of the dorsal part of a vertebra, consisting of a pair of pedicles, a pair of laminae, and seven processes (four articular processes, two transverse processes, and one spinous process)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Elmod1tm1a(EUCOMM)Hmgu/Elmod1tm1a(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Elmod1tm1a(EUCOMM)Hmgu/H

 MP:0005571 decreased lactate dehydrogenase level "less than the normal concentration of this enzyme, which catalyzes the interconversion of lactate and pyruvate" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Elmod1tm1a(EUCOMM)Hmgu/Elmod1tm1a(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Elmod1tm1a(EUCOMM)Hmgu/H

 MP:0010097 abnormal retinal blood vessel morphology "any structural anomaly of the blood vessels supplying the retina" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Epas1tm1b(EUCOMM)Hmgu/Epas1+
Genetic Background: C57BL/6N-Epas1tm1b(EUCOMM)Hmgu/H

 MP:0010378 increased respiratory quotient "increase in the ratio of the volume of carbon dioxide released to oxygen consumed by a body tissue or an organism compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Epas1tm1b(EUCOMM)Hmgu/Epas1+
Genetic Background: C57BL/6N-Epas1tm1b(EUCOMM)Hmgu/H

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Epas1tm1b(EUCOMM)Hmgu/Epas1+
Genetic Background: C57BL/6N-Epas1tm1b(EUCOMM)Hmgu/H

 MP:0011965 decreased total retina thickness "decreased width of the retina through the center plane" [MGI:csmith]
Show

Allelic Composition: Epas1tm1b(EUCOMM)Hmgu/Epas1+
Genetic Background: C57BL/6N-Epas1tm1b(EUCOMM)Hmgu/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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