ENSMUSG00000070644


Mus musculus

Features
Gene ID: ENSMUSG00000070644
  
Biological name :Etnk2
  
Synonyms : A7MCT6 / Ethanolamine kinase 2 / Etnk2
  
Possible biological names infered from orthology : Q9NVF9
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: E4
Gene start: 133363572
Gene end: 133380336
  
Corresponding Affymetrix probe sets: 10349932 (MoGene1.0st)   1437040_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000114272
Ensembl peptide - ENSMUSP00000122244
NCBI entrez gene - 214253     See in Manteia.
MGI - MGI:2443760
RefSeq - XM_006529364
RefSeq - NM_175443
RefSeq Peptide - NP_780652
swissprot - A7MCT6
swissprot - H9KV13
Ensembl - ENSMUSG00000070644
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 etnk2ENSDARG00000070213Danio rerio
 ETNK2ENSGALG00000000557Gallus gallus
 ETNK2ENSG00000143845Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Etnk1 / Q9D4V0 / Ethanolamine kinase 1 / Q9HBU6*ENSMUSG0000003027556
Chka / O54804 / Choline kinase alpha / P35790*ENSMUSG0000002484328
Chkb / O55229 / Choline/ethanolamine kinase / Q9Y259* / CHKB-CPT1B* / choline kinase beta* / CHKB-CPT1B readthrough (NMD candidate)*ENSMUSG0000002261728
AC137513.1 / CHKB* / Q9Y259* / CHKB-CPT1B* / choline kinase beta* / CHKB-CPT1B readthrough (NMD candidate)*ENSMUSG0000011646110


Protein motifs (from Interpro)
Interpro ID Name
 IPR011009  Protein kinase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IMP
 biological_processGO:0001890 placenta development IMP
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006646 phosphatidylethanolamine biosynthetic process IMP
 biological_processGO:0008654 phospholipid biosynthetic process IEA
 biological_processGO:0009791 post-embryonic development IMP
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0035264 multicellular organism growth IMP
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004305 ethanolamine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PE


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Crxtm1Clc/Crx+
Genetic Background: involves: 129S6/SvEvTac

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Pdgfrbtm1Sor/Pdgfrb+,Sgpl1Gt(ROSA)78Sor/Sgpl1Gt(ROSA)78Sor
Genetic Background: either: (involves: 129S4/SvJaeSor * 129S7/SvEvBrd) or (involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6)

 MP:0003718 maternal effect "expression of a phenotypic trait in an female animal s offspring that is dependent on the maternal genotype" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Crxtm1Clc/Crx+
Genetic Background: involves: 129S6/SvEvTac

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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