ENSMUSG00000071757


Mus musculus

Features
Gene ID: ENSMUSG00000071757
  
Biological name :Zhx2
  
Synonyms : Q8C0C0 / Zhx2 / zinc fingers and homeoboxes 2
  
Possible biological names infered from orthology : Q9Y6X8
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: D1
Gene start: 57694665
Gene end: 57839832
  
Corresponding Affymetrix probe sets: 10424213 (MoGene1.0st)   1455210_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000094164
NCBI entrez gene - 387609     See in Manteia.
MGI - MGI:2683087
RefSeq - XM_011245689
RefSeq - NM_199449
RefSeq - XM_011245688
RefSeq Peptide - NP_955520
swissprot - Q8C0C0
Ensembl - ENSMUSG00000071757
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zhx2aENSDARG00000055162Danio rerio
 ZHX2ENSGALG00000043827Gallus gallus
 ZHX2ENSG00000178764Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Zhx1 / P70121 / zinc fingers and homeoboxes 1 / Q9UKY1*ENSMUSG0000002236136
Zhx3 / Q8C0Q2 / zinc fingers and homeoboxes 3 / Q9H4I2*ENSMUSG0000003587733
Homez / homeobox and leucine zipper encoding / Q8IX15*ENSMUSG0000005715613


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IMP
 biological_processGO:0006402 mRNA catabolic process IDA
 biological_processGO:0035019 somatic stem cell population maintenance IDA
 biological_processGO:0045665 negative regulation of neuron differentiation IDA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003714 transcription corepressor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005416 abnormal circulating protein level "anomalous blood concentration of any of the macromolecules consisting of long chains of amino acids in peptide linkage" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Gnetm1.1Masn/Gnetm1.1Masn
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr