ENSG00000178764


Homo sapiens

Features
Gene ID: ENSG00000178764
  
Biological name :ZHX2
  
Synonyms : Q9Y6X8 / ZHX2 / zinc fingers and homeoboxes 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: q24.13
Gene start: 122781394
Gene end: 122974512
  
Corresponding Affymetrix probe sets: 1557706_at (Human Genome U133 Plus 2.0 Array)   203556_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000314709
Ensembl peptide - ENSP00000452720
NCBI entrez gene - 22882     See in Manteia.
OMIM - 609185
RefSeq - XM_011516932
RefSeq - NM_014943
RefSeq - XM_005250836
RefSeq - XM_005250837
RefSeq - XM_011516931
RefSeq Peptide - NP_055758
swissprot - Q9Y6X8
swissprot - H0YKA3
Ensembl - ENSG00000178764
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zhx2aENSDARG00000055162Danio rerio
 ZHX2ENSGALG00000043827Gallus gallus
 Zhx2ENSMUSG00000071757Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ZHX1 / Q9UKY1 / zinc fingers and homeoboxes 1ENSG0000016515638
ZHX3 / Q9H4I2 / zinc fingers and homeoboxes 3ENSG0000017430635
HOMEZ / Q8IX15 / homeobox and leucine zipper encodingENSG0000021527114


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR013087  Zinc finger C2H2-type
 IPR026939  At2g23090-like
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006402 mRNA catabolic process IEA
 biological_processGO:0035019 somatic stem cell population maintenance IEA
 biological_processGO:0045665 negative regulation of neuron differentiation IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0003714 transcription corepressor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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