ENSG00000174306


Homo sapiens

Features
Gene ID: ENSG00000174306
  
Biological name :ZHX3
  
Synonyms : Q9H4I2 / ZHX3 / zinc fingers and homeoboxes 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: q12
Gene start: 41178448
Gene end: 41317672
  
Corresponding Affymetrix probe sets: 212545_s_at (Human Genome U133 Plus 2.0 Array)   217367_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000453647
Ensembl peptide - ENSP00000453310
Ensembl peptide - ENSP00000454006
Ensembl peptide - ENSP00000454208
Ensembl peptide - ENSP00000312222
Ensembl peptide - ENSP00000362358
Ensembl peptide - ENSP00000399433
Ensembl peptide - ENSP00000400441
Ensembl peptide - ENSP00000401852
Ensembl peptide - ENSP00000403048
Ensembl peptide - ENSP00000405421
Ensembl peptide - ENSP00000415498
Ensembl peptide - ENSP00000443783
Ensembl peptide - ENSP00000452965
NCBI entrez gene - 23051     See in Manteia.
OMIM - 609598
RefSeq - XM_017027738
RefSeq - XM_011528708
RefSeq - XM_011528709
RefSeq - XM_011528711
RefSeq - XM_011528713
RefSeq - XM_011528714
RefSeq - XM_011528717
RefSeq - XM_011528718
RefSeq - XM_011528720
RefSeq - XM_017027736
RefSeq - XM_017027737
RefSeq - NM_015035
RefSeq - XM_005260341
RefSeq - XM_005260343
RefSeq - XM_006723748
RefSeq - XM_006723749
RefSeq - XM_011528701
RefSeq - XM_011528702
RefSeq - XM_011528703
RefSeq - XM_011528704
RefSeq - XM_011528705
RefSeq - XM_011528706
RefSeq - XM_011528707
RefSeq Peptide - NP_055850
swissprot - F6UBH9
swissprot - F6UQN6
swissprot - F6XGA7
swissprot - H0Y6F5
swissprot - H0YLR4
swissprot - H0YNY7
swissprot - A0A0A0MST6
swissprot - A0A0A0MSU5
swissprot - Q9H4I2
Ensembl - ENSG00000174306
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-232b12.5ENSDARG00000087186Danio rerio
 zhx3ENSDARG00000019774Danio rerio
 ZHX3ENSGALG00000039155Gallus gallus
 Zhx3ENSMUSG00000035877Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ZHX1 / Q9UKY1 / zinc fingers and homeoboxes 1ENSG0000016515633
ZHX2 / Q9Y6X8 / zinc fingers and homeoboxes 2ENSG0000017876430
HOMEZ / Q8IX15 / homeobox and leucine zipper encodingENSG0000021527114


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR013087  Zinc finger C2H2-type
 IPR024578  Homez, homeobox domain
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0045669 positive regulation of osteoblast differentiation IMP
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0003714 transcription corepressor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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