ENSG00000215271


Homo sapiens

Features
Gene ID: ENSG00000215271
  
Biological name :HOMEZ
  
Synonyms : homeobox and leucine zipper encoding / HOMEZ / Q8IX15
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q11.2
Gene start: 23272422
Gene end: 23299447
  
Corresponding Affymetrix probe sets: 231868_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000453979
Ensembl peptide - ENSP00000475307
Ensembl peptide - ENSP00000350049
NCBI entrez gene - 57594     See in Manteia.
OMIM - 608119
RefSeq - NM_020834
RefSeq Peptide - NP_065885
swissprot - Q8IX15
swissprot - U3KPW8
Ensembl - ENSG00000215271
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 homezaENSDARG00000054304Danio rerio
 homezbENSDARG00000024598Danio rerio
 HomezENSMUSG00000057156Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ZHX3 / Q9H4I2 / zinc fingers and homeoboxes 3ENSG0000017430625
ZHX1 / Q9UKY1 / zinc fingers and homeoboxes 1ENSG0000016515623
ZHX2 / Q9Y6X8 / zinc fingers and homeoboxes 2ENSG0000017876421


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR008422  Homeobox KN domain
 IPR009057  Homeobox-like domain superfamily
 IPR024578  Homez, homeobox domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IBA
 molecular_functionGO:0003714 transcription corepressor activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr