ENSMUSG00000072720


Mus musculus

Features
Gene ID: ENSMUSG00000072720
  
Biological name :Myo18b
  
Synonyms : Myo18b / myosin XVIIIB
  
Possible biological names infered from orthology : Q8IUG5
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: F
Gene start: 112688876
Gene end: 112896362
  
Corresponding Affymetrix probe sets: 10532563 (MoGene1.0st)   10532574 (MoGene1.0st)   10532576 (MoGene1.0st)   10532578 (MoGene1.0st)   10532580 (MoGene1.0st)   10532582 (MoGene1.0st)   10532584 (MoGene1.0st)   10532586 (MoGene1.0st)   10532588 (MoGene1.0st)   10532590 (MoGene1.0st)   10532592 (MoGene1.0st)   10532594 (MoGene1.0st)   10532596 (MoGene1.0st)   10532598 (MoGene1.0st)   10532616 (MoGene1.0st)   10532618 (MoGene1.0st)   10532620 (MoGene1.0st)   10532624 (MoGene1.0st)   10532626 (MoGene1.0st)   10532628 (MoGene1.0st)   1431813_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000138689
Ensembl peptide - ENSMUSP00000083810
NCBI entrez gene - 74376     See in Manteia.
MGI - MGI:1921626
RefSeq - NM_028901
RefSeq - XM_006535262
RefSeq Peptide - NP_083177
swissprot - E9PV66
swissprot - S4R2L2
Ensembl - ENSMUSG00000072720
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MYO18BENSGALG00000045218Gallus gallus
 MYO18BENSG00000133454Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Myo18a / Q9JMH9 / myosin XVIIIA / Q92614*ENSMUSG0000000063130


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR001609  Myosin head, motor domain
 IPR002928  Myosin tail
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR028561  Unconventional myosin-XVIIIb
 IPR036064  Class XVIII myosin, motor domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001570 vasculogenesis IMP
 biological_processGO:0001701 in utero embryonic development IMP
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0048739 cardiac muscle fiber development IMP
 cellular_componentGO:0016459 myosin complex IEA
 cellular_componentGO:0016461 unconventional myosin complex ISO
 cellular_componentGO:0030018 Z disc IDA
 cellular_componentGO:0031941 filamentous actin IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000278 abnormal myocardial fiber morphology "malformed or poorly developed cardiac muscle fibers, the multinucleated muscle cells of the heart" [J:18048]
Show

Allelic Composition: Ncor2tm1Rev/Ncor2tm1Rev
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0001634 internal hemorrhage "blood loss in the interior of the body due to vessel rupture or dysmorphology " [J:23170]
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Allelic Composition: Ncor2tm1Rev/Ncor2tm1Rev
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0004783 abnormal cardinal vein morphology "any structural anomaly of any of the four veins in the developing vertebrate embryo which run along each side of the vertebral column" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ncor2tm1Rev/Ncor2tm1Rev
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0005312 pericardial effusion "escape of fluid from blood vessels or lymphatics into the fibrous sac surrounding the heart" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Ncor2tm1Rev/Ncor2tm1Rev
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0005329 abnormal cardiac muscle morphology "anomalous structure of the involuntary muscle comprising the myocardium " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ncor2tm1Rev/Ncor2tm1Rev
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0008727 enlarged right atrium "increased size of the right upper chamber of the heart" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ncor2tm1Rev/Ncor2tm1Rev
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Ncor2tm1Rev/Ncor2tm1Rev
Genetic Background: involves: 129/Sv * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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