ENSMUSG00000073481


Mus musculus

Features
Gene ID: ENSMUSG00000073481
  
Biological name :Marc2
  
Synonyms : Marc2 / Mitochondrial amidoxime reducing component 2 / Q922Q1
  
Possible biological names infered from orthology : Q969Z3
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: H5
Gene start: 184813068
Gene end: 184846451
  
Corresponding Affymetrix probe sets: 10360848 (MoGene1.0st)   1416766_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000125374
Ensembl peptide - ENSMUSP00000066715
NCBI entrez gene - 67247     See in Manteia.
MGI - MGI:1914497
RefSeq - NM_133684
RefSeq - XM_006497194
RefSeq Peptide - NP_598445
swissprot - E0CZH6
swissprot - Q922Q1
Ensembl - ENSMUSG00000073481
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:110783ENSDARG00000070487Danio rerio
 MARC1ENSGALG00000009453Gallus gallus
 MARC2ENSG00000117791Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Marc1 / Q9CW42 / Mitochondrial amidoxime-reducing component 1 / Q5VT66*ENSMUSG0000002662161
Mocos / Q14CH1 / Molybdenum cofactor sulfurase / Q96EN8*ENSMUSG0000003961625


Protein motifs (from Interpro)
Interpro ID Name
 IPR005302  Molybdenum cofactor sulfurase, C-terminal
 IPR005303  MOSC, N-terminal beta barrel
 IPR011037  Pyruvate kinase-like, insert domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0042126 nitrate metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process ISO
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005741 mitochondrial outer membrane IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IDA
 cellular_componentGO:0005777 peroxisome IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0008940 nitrate reductase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0030151 molybdenum ion binding IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA
 molecular_functionGO:0043546 molybdopterin cofactor binding IEA


Pathways (from Reactome)
Pathway description
Phase I - Functionalization of compounds


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Hprttm1a(EUCOMM)Hmgu/Hprttm1a(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Hprttm1a(EUCOMM)Hmgu/Ieg

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000018042 Cyb5r3 / Q9DCN2 / NADH-cytochrome b5 reductase 3 NADH-cytochrome b5 reductase 3 membrane-bound form NADH-cytochrome b5 reductase 3 soluble form / P00387* / cytochrome b5 reductase 3*  / complex
 ENSMUSG00000026621 Marc1 / Q9CW42 / Mitochondrial amidoxime-reducing component 1 / Q5VT66*  / complex
 ENSMUSG00000031924 Cyb5b / Q9CQX2 / Cytochrome b5 type B / O43169*  / complex






 

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