ENSMUSG00000073609


Mus musculus

Features
Gene ID: ENSMUSG00000073609
  
Biological name :D2hgdh
  
Synonyms : D2hgdh / D-2-hydroxyglutarate dehydrogenase, mitochondrial / Q8CIM3
  
Possible biological names infered from orthology : D-2-hydroxyglutarate dehydrogenase / Q8N465
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: D
Gene start: 93824909
Gene end: 93852348
  
Corresponding Affymetrix probe sets: 10348889 (MoGene1.0st)   1437243_at (Mouse Genome 430 2.0 Array)   1437840_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000140181
Ensembl peptide - ENSMUSP00000095235
Ensembl peptide - ENSMUSP00000140506
Ensembl peptide - ENSMUSP00000108502
Ensembl peptide - ENSMUSP00000139812
Ensembl peptide - ENSMUSP00000139770
NCBI entrez gene - 98314     See in Manteia.
MGI - MGI:2138209
RefSeq - XM_006529970
RefSeq - XM_006529968
RefSeq - XM_006529973
RefSeq - XM_006529972
RefSeq - XM_006529971
RefSeq - NM_001310767
RefSeq - NM_178882
RefSeq - XM_017313036
RefSeq Peptide - NP_849213
RefSeq Peptide - NP_001297696
swissprot - Q8CIM3
swissprot - E9QN44
swissprot - A0A087WPG6
swissprot - A0A087WPK4
swissprot - A0A087WQG0
swissprot - A0A087WR78
Ensembl - ENSMUSG00000073609
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 d2hgdhENSDARG00000060210Danio rerio
 D2HGDHENSGALG00000039535Gallus gallus
 D2HGDHENSG00000180902Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004113  FAD-linked oxidase, C-terminal
 IPR006094  FAD linked oxidase, N-terminal
 IPR016164  FAD-linked oxidase-like, C-terminal
 IPR016166  FAD-binding, type 2
 IPR016167  FAD-binding, type 2, subdomain 1
 IPR016171  Vanillyl-alcohol oxidase, C-terminal subdomain 2
 IPR036318  FAD-binding, type 2-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010042 response to manganese ion IEA
 biological_processGO:0010043 response to zinc ion IEA
 biological_processGO:0019516 lactate oxidation IBA
 biological_processGO:0022904 respiratory electron transport chain IBA
 biological_processGO:0032025 response to cobalt ion IEA
 biological_processGO:0044267 cellular protein metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004458 D-lactate dehydrogenase (cytochrome) activity IBA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016614 oxidoreductase activity, acting on CH-OH group of donors IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IEA
 molecular_functionGO:0051990 (R)-2-hydroxyglutarate dehydrogenase activity IEA
 molecular_functionGO:0071949 FAD binding IBA


Pathways (from Reactome)
Pathway description
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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