ENSMUSG00000075232


Mus musculus

Features
Gene ID: ENSMUSG00000075232
  
Biological name :Amd1
  
Synonyms : Amd1 / P0DMN7 / S-adenosylmethionine decarboxylase proenzyme 1 S-adenosylmethionine decarboxylase 1 alpha chain S-adenosylmethionine decarboxylase 1 beta chain
  
Possible biological names infered from orthology : adenosylmethionine decarboxylase 1 / P17707
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: B1
Gene start: 40287458
Gene end: 40302186
  
Corresponding Affymetrix probe sets: 10368670 (MoGene1.0st)   10368748 (MoGene1.0st)   10447510 (MoGene1.0st)   10459389 (MoGene1.0st)   10512935 (MoGene1.0st)   1416835_s_at (Mouse Genome 430 2.0 Array)   1448484_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000151015
Ensembl peptide - ENSMUSP00000097528
NCBI entrez gene - 11702     See in Manteia.
MGI - MGI:88004
RefSeq - NM_009665
RefSeq Peptide - NP_033795
swissprot - A0A1L1SV28
swissprot - P0DMN7
Ensembl - ENSMUSG00000075232
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 amd1ENSDARG00000043856Danio rerio
 AMD1ENSGALG00000039575Gallus gallus
 AMD1ENSG00000123505Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Amd2 / D3Z6H8 / S-adenosylmethionine decarboxylase proenzyme 2 S-adenosylmethionine decarboxylase 2 alpha chain S-adenosylmethionine decarboxylase 2 beta chain / AMD1* / P17707* / adenosylm...ENSMUSG00000063953100


Protein motifs (from Interpro)
Interpro ID Name
 IPR001985  S-adenosylmethionine decarboxylase
 IPR016067  S-adenosylmethionine decarboxylase, core
 IPR018166  S-adenosylmethionine decarboxylase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IMP
 biological_processGO:0006557 S-adenosylmethioninamine biosynthetic process IEA
 biological_processGO:0006596 polyamine biosynthetic process IEA
 biological_processGO:0006597 spermine biosynthetic process IEA
 biological_processGO:0008295 spermidine biosynthetic process IEA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0004014 adenosylmethionine decarboxylase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016831 carboxy-lyase activity IEA
 molecular_functionGO:0019810 putrescine binding IBA


Pathways (from Reactome)
Pathway description
Metabolism of polyamines


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001730 embryonic growth arrest "the cessation of development beyond a particular stage" [J:17509]
Show

Allelic Composition: Fzd9tm1Sjp/Fzd9+
Genetic Background: involves: C57BL/6J

 MP:0011096 complete embryonic lethality before somite formation "death of all organisms of a given genotype in a population between the point of implantation and somite formation (Mus: E4.5 to less than E8)" [MGI:csmith]
Show

Allelic Composition: Fzd9tm1Sjp/Fzd9+
Genetic Background: involves: C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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