ENSMUSG00000090958


Mus musculus

Features
Gene ID: ENSMUSG00000090958
  
Biological name :Lrrc32
  
Synonyms : leucine rich repeat containing 32 / Lrrc32
  
Possible biological names infered from orthology : Q14392
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: E1
Gene start: 98489283
Gene end: 98502181
  
Corresponding Affymetrix probe sets: 10555174 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000146299
Ensembl peptide - ENSMUSP00000133205
Ensembl peptide - ENSMUSP00000145859
NCBI entrez gene - 434215     See in Manteia.
MGI - MGI:93882
RefSeq - XM_006507977
RefSeq - XM_006507979
RefSeq - NM_001113379
RefSeq - XM_006507978
RefSeq Peptide - NP_001106850
swissprot - G3XA59
swissprot - A0A0U1RQ93
Ensembl - ENSMUSG00000090958
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lrrc32ENSDARG00000040621Danio rerio
 LRRC32ENSGALG00000000818Gallus gallus
 LRRC32ENSG00000137507Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nrros / Q8BMT4 / Mus musculus negative regulator of reactive oxygen species (Nrros), transcript variant 2, mRNA. / Q86YC3* / negative regulator of reactive oxygen species*ENSMUSG0000005238431


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010628 positive regulation of gene expression IDA
 biological_processGO:0046007 negative regulation of activated T cell proliferation IDA
 biological_processGO:0050710 negative regulation of cytokine secretion IDA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0004946 abnormal regulatory T cell physiology "any functional anomaly of the specialized subpopulation of T cells that act to suppress activation of the immune system and thus maintain immune system homeostasis and prevent pathological self-reactivity; these may include T cells that express the CD8 transmembrane glycoprotein (CD8-positive T cells), those that express CD4 and CD25 (CD4-positive, CD25-positive regulatory T cells or "Tregs") and other T cell types that have suppressor function" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Azi2tm1Aki/Azi2tm1Aki,Tbkbp1tm1Aki/Tbkbp1tm1Aki
Genetic Background: Not Specified

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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