ENSMUSG00000092607


Mus musculus

Features
Gene ID: ENSMUSG00000092607
  
Biological name :Scnm1
  
Synonyms : Q8K136 / Scnm1 / Sodium channel modifier 1
  
Possible biological names infered from orthology : Q9BWG6
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: F2.1
Gene start: 95129536
Gene end: 95134011
  
Corresponding Affymetrix probe sets: 10500091 (MoGene1.0st)   1428364_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000133769
Ensembl peptide - ENSMUSP00000134337
NCBI entrez gene - 69269     See in Manteia.
MGI - MGI:1341284
RefSeq - XM_017319716
RefSeq - NM_001163573
RefSeq - NM_027013
RefSeq - XM_017319715
RefSeq Peptide - NP_081289
RefSeq Peptide - NP_001157045
swissprot - Q8K136
swissprot - A0A0R4J262
Ensembl - ENSMUSG00000092607
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 scnm1ENSDARG00000003027Danio rerio
 SCNM1ENSGALG00000046607Gallus gallus
 SCNM1ENSG00000163156Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR031622  Sodium channel modifier 1, zinc-finger
 IPR031625  Sodium channel modifier 1, acidic C-terminal domain
 IPR033570  Sodium channel modifier 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0008380 RNA splicing IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0019899 enzyme binding ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000747 muscle weakness "loss of muscle strength" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Scn8amed-J/Scn8amed-J,Scnm1s/Scnm1s
Genetic Background: involves: C57BL/6J * STOCK Krt71Ca

 MP:0000753 paralysis "loss of power of voluntary movement in a muscle through injury or disease of its nerve supply" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Scn8amed-J/Scn8amed-J,Scnm1s/Scnm1s
Genetic Background: involves: C57BL/6J

 MP:0000755 hindlimb paralysis "loss of power of voluntary movement in the muscles of the hindlimb through injury or disease of it or its nerve supply" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Scn8amed-J/Scn8amed-J,Scnm1tm1.1Mm/Scnm1tm1.1Mm
Genetic Background: involves: C57BL/6 * FVB * SJL * STOCK Krt71Ca

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: H6pdtm1Pmst/H6pdtm1Pmst
Genetic Background: involves: 129P2/OlaHsd

 MP:0001393 ataxia "inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231]
Show

Allelic Composition: Scn8amed-J/Scn8amed-J,Scnm1s/Scnm1s
Genetic Background: involves: C57BL/6J

 MP:0002082 postnatal lethality "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Scn8amed-J/Scn8amed-J,Scnm1m1R/Scnm1m1R
Genetic Background: involves: C57BL/6 * STOCK Krt71Ca

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Scn8amed-J/Scn8amed-J,Scnm1s/Scnm1s
Genetic Background: involves: C57BL/6J

Allelic Composition: Scn8amed-J/Scn8amed-J,Scnm1tm1.1Mm/Scnm1tm1.1Mm
Genetic Background: involves: C57BL/6 * FVB * SJL * STOCK Krt71Ca

Allelic Composition: Scn8amed-J/Scn8amed-J,Scnm1s/Scnm1s
Genetic Background: involves: C57BL/6J * STOCK Krt71Ca

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: H6pdtm1Pmst/H6pdtm1Pmst
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Scnm1tm1.1Mm/Scnm1tm1.1Mm
Genetic Background: involves: 129S6SvEvTac * C57BL/6 * FVB * SJL

Allelic Composition: Scnm1tm1.1Mm/Scnm1tm1.1Mm
Genetic Background: involves: C3HeB/FeJ * C57BL/6 * FVB * SJL

 MP:0002269 muscular atrophy "a wasting of muscle tissue resulting in a derangement of the muscle fibers; occurs with age, immobilization, weightlessness, malnutrition or denervation" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
Show

Allelic Composition: Scn8amed-J/Scn8amed-J,Scnm1s/Scnm1s
Genetic Background: involves: C57BL/6J

 MP:0005323 dystonia "impairment of muscle tone resulting in prolonged muscle contraction and involuntary movements such as repetitive movements, or twisting or writhing of the limbs" [J:84533]
Show

Allelic Composition: Scn8amed-J/Scn8amed-J,Scnm1s/Scnm1s
Genetic Background: involves: C57BL/6J

 MP:0005621 abnormal cell physiology "aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
Show

Allelic Composition: Scn8amed-J/Scn8amed-J,Scnm1tm1.1Mm/Scnm1tm1.1Mm
Genetic Background: involves: C57BL/6 * FVB * SJL * STOCK Krt71Ca

Allelic Composition: Scn8amed-J/Scn8amed-J,Scnm1s/Scnm1s
Genetic Background: involves: C57BL/6J * STOCK Krt71Ca

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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