ENSDARG00000001897


Danio rerio

Features
Gene ID: ENSDARG00000001897
  
Biological name :man2b1
  
Synonyms : man2b1 / mannosidase, alpha, class 2B, member 1
  
Possible biological names infered from orthology : AC010422.3 / AC010422.5 / Lysosomal alpha-mannosidase / O00754 / O09159
  
Species: Danio rerio
  
Chr. number: 11
Strand: -1
Band:
Gene start: 31258116
Gene end: 31276080
  
Corresponding Affymetrix probe sets: Dr.5214.2.A1_at (Zebrafish Array)   NM_001014332_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000014955
Ensembl peptide - ENSDARP00000117668
NCBI entrez gene - 541519     See in Manteia.
RefSeq - XM_005169363
RefSeq - NM_001014332
RefSeq Peptide - NP_001014354
swissprot - F1QTT0
swissprot - E9QDW2
ZFIN ID - ZDB-GENE-050327-52
Ensembl - ENSDARG00000001897
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AC010422.3ENSG00000269242Homo sapiens
 AC010422.5ENSG00000269590Homo sapiens
 MAN2B1ENSG00000104774Homo sapiens
 Man2b1ENSMUSG00000005142Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
man2b2 / mannosidase, alpha, class 2B, member 2 / Q9Y2E5* / Mrfap1* / Q9CQL7* / MORF4 family-associated protein 1 *ENSDARG0000007946326
man2a1 / mannosidase, alpha, class 2A, member 1 / P27046* / Q16706* / Alpha-mannosidase 2 *ENSDARG0000010220026
man2a2 / mannosidase, alpha, class 2A, member 2 / P49641* / Q8BRK9* / Alpha-mannosidase 2x *ENSDARG0000006310125


Protein motifs (from Interpro)
Interpro ID Name
 IPR000602  Glycoside hydrolase family 38, N-terminal domain
 IPR011013  Galactose mutarotase-like domain superfamily
 IPR011330  Glycoside hydrolase/deacetylase, beta/alpha-barrel
 IPR011682  Glycosyl hydrolase family 38, C-terminal
 IPR015341  Glycoside hydrolase family 38, central domain
 IPR027291  Glycoside hydrolase 38, N-terminal domain superfamily
 IPR028995  Glycoside hydrolase families 57/38, central domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006013 mannose metabolic process IEA
 biological_processGO:0006517 protein deglycosylation IBA
 biological_processGO:0008152 metabolic process IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004559 alpha-mannosidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Lysosomal oligosaccharide catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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