ENSDARG00000063101


Danio rerio

Features
Gene ID: ENSDARG00000063101
  
Biological name :man2a2
  
Synonyms : man2a2 / mannosidase, alpha, class 2A, member 2
  
Possible biological names infered from orthology : Alpha-mannosidase 2x / P49641 / Q8BRK9
  
Species: Danio rerio
  
Chr. number: 25
Strand: 1
Band:
Gene start: 8662469
Gene end: 8742650
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000129200
Ensembl peptide - ENSDARP00000154311
NCBI entrez gene - 100333987     See in Manteia.
swissprot - E7EYL2
ZFIN ID - ZDB-GENE-110331-1
Ensembl - ENSDARG00000063101
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MAN2A2ENSGALG00000033790Gallus gallus
 MAN2A2ENSG00000196547Homo sapiens
 Man2a2ENSMUSG00000038886Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
man2a1 / mannosidase, alpha, class 2A, member 1 / P27046* / Q16706* / Alpha-mannosidase 2 *ENSDARG0000010220056
man2b1 / mannosidase, alpha, class 2B, member 1 / O09159* / O00754* / AC010422.5* / AC010422.3* / Lysosomal alpha-mannosidase *ENSDARG0000000189721
man2b2 / mannosidase, alpha, class 2B, member 2 / Q9Y2E5* / Mrfap1* / Q9CQL7* / MORF4 family-associated protein 1 *ENSDARG0000007946321


Protein motifs (from Interpro)
Interpro ID Name
 IPR000602  Glycoside hydrolase family 38, N-terminal domain
 IPR011013  Galactose mutarotase-like domain superfamily
 IPR011330  Glycoside hydrolase/deacetylase, beta/alpha-barrel
 IPR011682  Glycosyl hydrolase family 38, C-terminal
 IPR015341  Glycoside hydrolase family 38, central domain
 IPR027291  Glycoside hydrolase 38, N-terminal domain superfamily
 IPR028995  Glycoside hydrolase families 57/38, central domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006013 mannose metabolic process IBA
 biological_processGO:0006491 N-glycan processing IBA
 biological_processGO:0006517 protein deglycosylation IBA
 biological_processGO:0008152 metabolic process IEA
 cellular_componentGO:0000139 Golgi membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004559 alpha-mannosidase activity IBA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Reactions specific to the complex N-glycan synthesis pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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