ENSDARG00000002305


Danio rerio

Features
Gene ID: ENSDARG00000002305
  
Biological name :me3
  
Synonyms : malic enzyme 3, NADP(+)-dependent, mitochondrial / me3
  
Possible biological names infered from orthology : malic enzyme 3 / NADP-dependent malic enzyme, mitochondrial / Q16798 / Q8BMF3
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 34246384
Gene end: 34260214
  
Corresponding Affymetrix probe sets: Dr.7335.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000006882
NCBI entrez gene - 492719     See in Manteia.
RefSeq - NM_001089356
RefSeq Peptide - NP_001082825
swissprot - A4QPA0
ZFIN ID - ZDB-GENE-041111-294
Ensembl - ENSDARG00000002305
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ME3ENSGALG00000017246Gallus gallus
 ME3ENSG00000151376Homo sapiens
 Me3ENSMUSG00000030621Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
me1 / malic enzyme 1, NADP(+)-dependent, cytosolic / P06801* / P48163* / malic enzyme 1* / NADP-dependent malic enzyme *ENSDARG0000005321571
me2 / malic enzyme 2, NAD(+)-dependent, mitochondrial / P23368* / Q99KE1* / malic enzyme 2* / NAD-dependent malic enzyme, mitochondrial *ENSDARG0000010071856


Protein motifs (from Interpro)
Interpro ID Name
 IPR001891  Malic oxidoreductase
 IPR012301  Malic enzyme, N-terminal domain
 IPR012302  Malic enzyme, NAD-binding
 IPR016040  NAD(P)-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006090 pyruvate metabolic process IBA
 biological_processGO:0006108 malate metabolic process IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IBA
 molecular_functionGO:0004470 malic enzyme activity IEA
 molecular_functionGO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity IEA
 molecular_functionGO:0004473 malate dehydrogenase (decarboxylating) (NADP+) activity IBA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051287 NAD binding IEA


Pathways (from Reactome)
Pathway description
Citric acid cycle (TCA cycle)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000002305 me3 / malic enzyme 3, NADP(+)-dependent, mitochondrial / Q16798* / Q8BMF3* / malic enzyme 3* / NADP-dependent malic enzyme, mitochondrial *  / complex






 

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