ENSDARG00000002731


Danio rerio

Features
Gene ID: ENSDARG00000002731
  
Biological name :sdc2
  
Synonyms : sdc2 / syndecan 2
  
Possible biological names infered from orthology : P34741 / P43407
  
Species: Danio rerio
  
Chr. number: 19
Strand: -1
Band:
Gene start: 47191005
Gene end: 47276297
  
Corresponding Affymetrix probe sets: Dr.12393.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000115190
swissprot - Q90ZY9
ZFIN ID - ZDB-GENE-021206-3
Ensembl - ENSDARG00000002731
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SDC2ENSGALG00000031424Gallus gallus
 SDC2ENSG00000169439Homo sapiens
 Sdc2ENSMUSG00000022261Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sdc4 / syndecan 4 / O35988* / P31431*ENSDARG0000005990630


Protein motifs (from Interpro)
Interpro ID Name
 IPR001050  Syndecan
 IPR003585  Neurexin/syndecan/glycophorin C
 IPR027789  Syndecan/Neurexin domain
 IPR030479  Syndecan, conserved site
 IPR031201  Syndecan-2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002040 sprouting angiogenesis IMP
 biological_processGO:0048565 digestive tract development IMP
 biological_processGO:0048813 dendrite morphogenesis IBA
 biological_processGO:0055113 epiboly involved in gastrulation with mouth forming second IMP
 biological_processGO:0060973 cell migration involved in heart development IMP
 biological_processGO:0070121 Kupffer"s vesicle development IMP
 biological_processGO:0097435 supramolecular fiber organization IMP
 cellular_componentGO:0009986 cell surface IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
A tetrasaccharide linker sequence is required for GAG synthesis
HS-GAG biosynthesis
HS-GAG degradation
Cell surface interactions at the vascular wall
Syndecan interactions
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
EPHB-mediated forward signaling
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle decreased size , abnormal
Kupffers vesicle malformed , abnormal
Kupffers vesicle physical object quality , abnormal
Kupffers vesicle motile cilium decreased length , abnormal
Kupffers vesicle motile cilium decreased amount , abnormal
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 ZFA:0000023 forerunner cell group forerunner cell group decreased size , abnormal
forerunner cell group physical object quality , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000084 yolk yolk increased size , abnormal
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 ZFA:0000106 extension extension morphology , abnormal
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 ZFA:0000114 heart heart symmetry , abnormal
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 ZFA:0000121 lateral plate mesoderm lateral plate mesoderm symmetry , abnormal
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 ZFA:0001094 whole organism whole organism decreased size , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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