ENSDARG00000003411


Danio rerio

Features
Gene ID: ENSDARG00000003411
  
Biological name :foxa2
  
Synonyms : forkhead box A2 / foxa2
  
Possible biological names infered from orthology : Mus musculus forkhead box A2 (Foxa2), transcript variant 3, mRNA. / P35583 / Q9Y261
  
Species: Danio rerio
  
Chr. number: 17
Strand: -1
Band:
Gene start: 42565998
Gene end: 42568498
  
Corresponding Affymetrix probe sets: Dr.483.1.S1_at (Zebrafish Array)   NM_130949_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000007827
NCBI entrez gene - 30126     See in Manteia.
RefSeq - NM_130949
RefSeq Peptide - NP_571024
swissprot - F1Q819
ZFIN ID - ZDB-GENE-980526-404
Ensembl - ENSDARG00000003411
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FOXA2ENSGALG00000030889Gallus gallus
 FOXA2ENSG00000125798Homo sapiens
 Foxa2ENSMUSG00000037025Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
foxa1 / forkhead box A1ENSDARG0000010213860
foxa3 / forkhead box A3 / P35584* / P55318* / Hepatocyte nuclear factor 3-gamma *ENSDARG0000001278848
foxa / forkhead box A sequenceENSDARG0000008709432
Q9DE25 / foxc1a / forkhead box C1a / FOXC1* / Q12948* / Q61572* / forkhead box C1* / Forkhead box protein C1 *ENSDARG0000009148126
foxb1b / forkhead box B1b / FOXB1* / Q64732* / Q99853* / forkhead box B1* / Forkhead box protein B1 *ENSDARG0000005365025
foxb1a / forkhead box B1a / FOXB1* / Q64732* / Q99853* / forkhead box B1* / Forkhead box protein B1 *ENSDARG0000008904225
Q9DE24 / foxc1b / forkhead box C1b / FOXC1* / Q12948* / Q61572* / forkhead box C1* / Forkhead box protein C1 *ENSDARG0000005539824
foxb2 / forkhead box B2 / Q5VYV0* / Q64733* / Forkhead box protein B2 *ENSDARG0000003747523
foxi3b / forkhead box I3b / FOXI1* / Q12951* / Q922I5* / forkhead box I1* / Forkhead box protein I1 *ENSDARG0000000955022
foxi2 / forkhead box I2 / FOXI3* / Q6ZQN5* / A8MTJ6* / forkhead box I3*ENSDARG0000006971522
foxi1 / forkhead box i1ENSDARG0000010456621
foxl1 / forkhead box L1 / Q12952* / Q64731* / Forkhead box protein L1 *ENSDARG0000000813320
foxl2a / forkhead box L2a / FOXL2* / O88470* / P58012* / forkhead box L2* / Forkhead box protein L2 *ENSDARG0000004218019
foxi3a / forkhead box I3a / FOXI1* / Q12951* / Q922I5* / forkhead box I1* / Forkhead box protein I1 *ENSDARG0000005592619
foxl2b / forkhead box L2b / FOXL2* / P58012* / forkhead box L2*ENSDARG0000006841719
zgc:194189ENSDARG0000000801017


Protein motifs (from Interpro)
Interpro ID Name
 IPR001766  Fork head domain
 IPR011991  ArsR-like helix-turn-helix domain
 IPR013638  Fork-head N-terminal
 IPR018122  Fork head domain conserved site1
 IPR018533  Forkhead box protein, C-terminal
 IPR030456  Fork head domain conserved site 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000022 floor plate floor plate morphology , abnormal
floor plate undifferentiated , abnormal
Show

 ZFA:0000123 liver liver decreased size , abnormal
liver aplastic , abnormal
Show

 ZFA:0000140 pancreas pancreas aplastic , abnormal
pancreas decreased size , abnormal
Show

 ZFA:0001094 whole organism whole organism lethal (sensu genetics) , abnormal
whole organism viability , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved , abnormal
post-vent region curved ventral , abnormal
Show

 ZFA:0001249 exocrine pancreas exocrine pancreas decreased size , abnormal
Show

 ZFA:0001338 intestine intestine goblet cell decreased amount , abnormal
Show

 ZFA:0009094 goblet cell goblet cell cell maturation disrupted , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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