ENSDARG00000068417


Danio rerio

Features
Gene ID: ENSDARG00000068417
  
Biological name :foxl2b
  
Synonyms : forkhead box L2b / foxl2b
  
Possible biological names infered from orthology : forkhead box L2 / Forkhead box protein L2 / FOXL2 / O88470 / P58012
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 58256276
Gene end: 58257624
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000089710
NCBI entrez gene - 100149117     See in Manteia.
RefSeq - NM_001317761
RefSeq Peptide - NP_001304690
swissprot - F1QJW8
swissprot - A0A0N9JT62
ZFIN ID - ZDB-GENE-170803-1
Ensembl - ENSDARG00000068417
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FOXL2ENSGALG00000029282Gallus gallus
 FOXL2ENSG00000183770Homo sapiens
 Foxl2ENSMUSG00000050397Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
foxl2a / forkhead box L2a / FOXL2* / O88470* / P58012* / forkhead box L2* / Forkhead box protein L2 *ENSDARG0000004218072
zgc:194189ENSDARG0000000801043
Q9DE24 / foxc1b / forkhead box C1b / FOXC1* / Q12948* / Q61572* / forkhead box C1* / Forkhead box protein C1 *ENSDARG0000005539831
Q9DE25 / foxc1a / forkhead box C1a / FOXC1* / Q12948* / Q61572* / forkhead box C1* / Forkhead box protein C1 *ENSDARG0000009148131
foxi3b / forkhead box I3b / FOXI1* / Q12951* / Q922I5* / forkhead box I1* / Forkhead box protein I1 *ENSDARG0000000955030
foxi2 / forkhead box I2 / FOXI3* / Q6ZQN5* / A8MTJ6* / forkhead box I3*ENSDARG0000006971530
foxl1 / forkhead box L1 / Q12952* / Q64731* / Forkhead box protein L1 *ENSDARG0000000813329
foxi3a / forkhead box I3a / FOXI1* / Q12951* / Q922I5* / forkhead box I1* / Forkhead box protein I1 *ENSDARG0000005592628
foxa2 / forkhead box A2 / P35583* / Q9Y261* / Mus musculus forkhead box A2 (Foxa2), transcript variant 3, mRNA.*ENSDARG0000000341127
foxi1 / forkhead box i1ENSDARG0000010456626
foxb2 / forkhead box B2 / Q5VYV0* / Q64733* / Forkhead box protein B2 *ENSDARG0000003747525
foxa / forkhead box A sequenceENSDARG0000008709425
foxa1 / forkhead box A1ENSDARG0000010213825
foxa3 / forkhead box A3 / P35584* / P55318* / Hepatocyte nuclear factor 3-gamma *ENSDARG0000001278824
foxb1b / forkhead box B1b / FOXB1* / Q64732* / Q99853* / forkhead box B1* / Forkhead box protein B1 *ENSDARG0000005365024
foxb1a / forkhead box B1a / FOXB1* / Q64732* / Q99853* / forkhead box B1* / Forkhead box protein B1 *ENSDARG0000008904224


Protein motifs (from Interpro)
Interpro ID Name
 IPR001766  Fork head domain
 IPR011991  ArsR-like helix-turn-helix domain
 IPR018122  Fork head domain conserved site1
 IPR030456  Fork head domain conserved site 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0009653 anatomical structure morphogenesis IBA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0048496 maintenance of animal organ identity IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
SUMOylation of transcription factors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000403 ovary ovary morphology , abnormal
ovary increased amount , abnormal
ovary senescent , abnormal
ovary decreased amount , abnormal
ovary spermatogenesis increased occurrence , abnormal
ovary maintenance of animal organ identity disrupted , abnormal
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 ZFA:0000413 gonad gonad increased amount , abnormal
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 ZFA:0000598 testis testis increased amount , abnormal
testis decreased amount , abnormal
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 ZFA:0001094 whole organism whole organism ovary male , abnormal
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 ZFA:0001109 oocyte oocyte reproductive senescence increased occurrence , abnormal
oocyte degenerate , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000007438 ube2ib / Q9W6H5 / ubiquitin-conjugating enzyme E2Ib / UBE2I* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction
 ENSDARG00000044267 sumo1 / Q7SZR5 / small ubiquitin-like modifier 1 / P63166* / P63165* / Small ubiquitin-related modifier 1 *  / complex / reaction
 ENSDARG00000052649 Q9DDJ0 / ube2ia / ubiquitin-conjugating enzyme E2Ia / UBE2I* / P63280* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction






 

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